ABCB9 (ATP binding cassette subfamily B member 9)

2008-03-01  

Identity

HGNC
ABCB9
LOCATION
12q24.31
LOCUSID
23457
ALIAS
EST122234,TAPL
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23457
MIM: 605453
HGNC: 50
Ensembl: ENSG00000150967

Variants:

dbSNP: 23457
ClinVar: 23457
TCGA: ENSG00000150967
COSMIC: ABCB9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000150967ENST00000280560Q9NP78
ENSG00000150967ENST00000280560A0A024RBU1
ENSG00000150967ENST00000344275Q9NP78
ENSG00000150967ENST00000346530Q9NP78
ENSG00000150967ENST00000392439Q9NP78
ENSG00000150967ENST00000392439A0A024RBU1
ENSG00000150967ENST00000426173H7C478
ENSG00000150967ENST00000442028Q6P2Q0
ENSG00000150967ENST00000442833Q9NP78
ENSG00000150967ENST00000536976F5H5F9
ENSG00000150967ENST00000537276F5H0G0
ENSG00000150967ENST00000540285Q9NP78
ENSG00000150967ENST00000540971F5GX86
ENSG00000150967ENST00000541424F5GXZ5
ENSG00000150967ENST00000542448F5GYI2
ENSG00000150967ENST00000542678Q9NP78
ENSG00000150967ENST00000542678A0A024RBU1
ENSG00000150967ENST00000543935F5H5I5
ENSG00000150967ENST00000545373F5H4Y2
ENSG00000150967ENST00000546077F5H5Q0
ENSG00000150967ENST00000546289F5H7U2

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
ABC transportersKEGGko02010
ABC transportersKEGGhsa02010
LysosomeKEGGko04142
LysosomeKEGGhsa04142
Transmembrane transport of small moleculesREACTOMER-HSA-382551
ABC-family proteins mediated transportREACTOMER-HSA-382556

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
308771952019Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues.12
308771952019Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues.12
303531402018Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL.4
303531402018Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL.4
240139302013Conformational stabilization of the membrane embedded targeting domain of the lysosomal peptide transporter TAPL for solution NMR.3
240139302013Conformational stabilization of the membrane embedded targeting domain of the lysosomal peptide transporter TAPL for solution NMR.3
226416972012The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2.18
226416972012The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2.18
212125142011Transporter associated with antigen processing-like (ABCB9) stably expressed in Chinese hamster ovary-K1 cells is sorted to the microdomains of lysosomal membranes.3
212125142011Transporter associated with antigen processing-like (ABCB9) stably expressed in Chinese hamster ovary-K1 cells is sorted to the microdomains of lysosomal membranes.3
203778232010Tuning the cellular trafficking of the lysosomal peptide transporter TAPL by its N-terminal domain.17
203778232010Tuning the cellular trafficking of the lysosomal peptide transporter TAPL by its N-terminal domain.17
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
181759332008Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells.2

Citation

Dessen P

ABCB9 (ATP binding cassette subfamily B member 9)

Atlas Genet Cytogenet Oncol Haematol. 2008-03-01

Online version: http://atlasgeneticsoncology.org/gene/50059/favicon/js/favicon/manifest.json