POLR1G (RNA polymerase I subunit G)

2008-05-01  

Identity

HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
ASE-1,ASE1,CAST,CD3EAP,PAF49,RPA34
FUSION GENES

Other Information

Locus ID:

NCBI: 10849
MIM: 107325
HGNC: 24219
Ensembl: ENSG00000117877

Variants:

dbSNP: 10849
ClinVar: 10849
TCGA: ENSG00000117877
COSMIC: POLR1G

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000117877ENST00000309424O15446
ENSG00000117877ENST00000589804O15446
ENSG00000117877ENST00000590794K7EMH2
ENSG00000117877ENST00000592852K7EQC8

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase I, RNA Polymerase III, and Mitochondrial TranscriptionREACTOMER-HSA-504046
RNA Polymerase I TranscriptionREACTOMER-HSA-73864
RNA Polymerase I Promoter ClearanceREACTOMER-HSA-73854
RNA Polymerase I Transcription InitiationREACTOMER-HSA-73762
RNA Polymerase I Promoter EscapeREACTOMER-HSA-73772
RNA Polymerase I Chain ElongationREACTOMER-HSA-73777
RNA Polymerase I Transcription TerminationREACTOMER-HSA-73863
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
Negative epigenetic regulation of rRNA expressionREACTOMER-HSA-5250941
NoRC negatively regulates rRNA expressionREACTOMER-HSA-427413
Positive epigenetic regulation of rRNA expressionREACTOMER-HSA-5250913
B-WICH complex positively regulates rRNA expressionREACTOMER-HSA-5250924

References

Pubmed IDYearTitleCitations
365266752023STAT3 potentiates RNA polymerase I-directed transcription and tumor growth by activating RPA34 expression.0
371473502023Common variants of pro-inflammatory gene IL1B and interactions with PPP1R13L and POLR1G in relation to lung cancer among Northeast Chinese.3
373567162023PAF49: An RNA Polymerase I subunit essential for rDNA transcription and stabilization of PAF53.0
365266752023STAT3 potentiates RNA polymerase I-directed transcription and tumor growth by activating RPA34 expression.0
371473502023Common variants of pro-inflammatory gene IL1B and interactions with PPP1R13L and POLR1G in relation to lung cancer among Northeast Chinese.3
373567162023PAF49: An RNA Polymerase I subunit essential for rDNA transcription and stabilization of PAF53.0
353514592022TP53 common variants and interaction with PPP1R13L and CD3EAP SNPs and lung cancer risk and smoking behavior in a Chinese population.3
353514592022TP53 common variants and interaction with PPP1R13L and CD3EAP SNPs and lung cancer risk and smoking behavior in a Chinese population.3
296202552018Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment.4
301288862018GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population.6
296202552018Different splicing isoforms of ERCC1 affect the expression of its overlapping genes CD3EAP and PPP1R13L, and indicate a potential application in non-small cell lung cancer treatment.4
301288862018GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population.6
28870783201719p13.3-GADD45B common variants and 19q13.3-PPP1R13L and 19q13.3-CD3EAP in lung cancer risk among Chinese.5
28870783201719p13.3-GADD45B common variants and 19q13.3-PPP1R13L and 19q13.3-CD3EAP in lung cancer risk among Chinese.5
265633752016Association and interaction of NFKB1 rs28362491 insertion/deletion ATTG polymorphism and PPP1R13L and CD3EAP related to lung cancer risk in a Chinese population.9

Citation

Dessen P

POLR1G (RNA polymerase I subunit G)

Atlas Genet Cytogenet Oncol Haematol. 2008-05-01

Online version: http://atlasgeneticsoncology.org/gene/50105/js/haematological-explorer/meetings/