ANXA6 (annexin A6)

2008-07-01  

Identity

HGNC
ANXA6
LOCATION
5q33.1
LOCUSID
309
ALIAS
ANX6,CBP68,CPB-II,p68,p70
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 309
MIM: 114070
HGNC: 544
Ensembl: ENSG00000197043

Variants:

dbSNP: 309
ClinVar: 309
TCGA: ENSG00000197043
COSMIC: ANXA6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197043ENST00000354546P08133
ENSG00000197043ENST00000354546A0A0S2Z2Z6
ENSG00000197043ENST00000377751E7EMC6
ENSG00000197043ENST00000517486E5RFF0
ENSG00000197043ENST00000517677E5RI05
ENSG00000197043ENST00000517757E5RJF5
ENSG00000197043ENST00000519644E5RIU8
ENSG00000197043ENST00000521512E5RK69
ENSG00000197043ENST00000521749E5RK63
ENSG00000197043ENST00000522664H0YC77
ENSG00000197043ENST00000523164E5RJR0
ENSG00000197043ENST00000523714P08133

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Muscle contractionREACTOMER-HSA-397014
Smooth Muscle ContractionREACTOMER-HSA-445355

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383807832024Annexin A6 mitigates neurological deficit in ischemia/reperfusion injury by promoting synaptic plasticity.0
385661332024SUMOylation of annexin A6 retards cell migration and tumor growth by suppressing RHOU/AKT1-involved EMT in hepatocellular carcinoma.0
383807832024Annexin A6 mitigates neurological deficit in ischemia/reperfusion injury by promoting synaptic plasticity.0
385661332024SUMOylation of annexin A6 retards cell migration and tumor growth by suppressing RHOU/AKT1-involved EMT in hepatocellular carcinoma.0
369580132023Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish.3
372042942023Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair.7
373119532023Comprehensive analysis the diagnosis, malignant progression and immune infiltrate of ANXA6 in prostate cancer.0
369580132023Annexin-A5 and annexin-A6 silencing prevents metastasis of breast cancer cells in zebrafish.3
372042942023Annexin A6 mediates calcium-dependent exosome secretion during plasma membrane repair.7
373119532023Comprehensive analysis the diagnosis, malignant progression and immune infiltrate of ANXA6 in prostate cancer.0
346732072022CRISPR-Cas9 mediated knockout of AnxA6 gene enhances influenza A virus replication in low-permissive HEK293FT cell line.2
350224652022Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions.7
346732072022CRISPR-Cas9 mediated knockout of AnxA6 gene enhances influenza A virus replication in low-permissive HEK293FT cell line.2
350224652022Annexin A6 and NPC1 regulate LDL-inducible cell migration and distribution of focal adhesions.7
335826722021The Impact of ANxA6 Gene Polymorphism on the Efficacy of Methotrexate Treatment in Psoriasis Patients.5

Citation

Dessen P

ANXA6 (annexin A6)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50196/img/js/lib/haematological-explorer/