DPPA2 (developmental pluripotency associated 2)

2008-09-01  

Identity

HGNC
DPPA2
LOCATION
3q13.13
LOCUSID
151871
ALIAS
CT100,ECAT15-2,PESCRG1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 151871
MIM: 614445
HGNC: 19197
Ensembl: ENSG00000163530

Variants:

dbSNP: 151871
ClinVar: 151871
TCGA: ENSG00000163530
COSMIC: DPPA2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163530ENST00000478945Q7Z7J5

Expression (GTEx)

0
1
2
3
4
5
6
7
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
333160322021Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region.8
338624602021SPOP suppresses testicular germ cell tumors progression through ubiquitination and degradation of DPPA2.0
347216602021Transcription Factor CTCFL Promotes Cell Proliferation, Migration, and Invasion in Gastric Cancer via Activating DPPA2.3
333160322021Dppa2/4 as a trigger of signaling pathways to promote zygote genome activation by binding to CG-rich region.8
338624602021SPOP suppresses testicular germ cell tumors progression through ubiquitination and degradation of DPPA2.0
347216602021Transcription Factor CTCFL Promotes Cell Proliferation, Migration, and Invasion in Gastric Cancer via Activating DPPA2.3
254970062015Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer.5
267451022015DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis.4
254970062015Diagnostic clinical relevance of developmental pluripotency-associated 2 (DPPA2) in colorectal cancer.5
267451022015DPPA2 Protein Expression is Associated with Gastric Cancer Metastasis.4
245324292014Aberrant expression of DPPA2 and HIWI genes in colorectal cancer and their impacts on poor prognosis.15
245324292014Aberrant expression of DPPA2 and HIWI genes in colorectal cancer and their impacts on poor prognosis.15
239637362013Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.17
239637362013Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.17
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

DPPA2 (developmental pluripotency associated 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-09-01

Online version: http://atlasgeneticsoncology.org/gene/50321/haematological-explorer/humanGenome