NPNT (nephronectin)

2008-10-01  

Identity

HGNC
NPNT
LOCATION
4q24
LOCUSID
255743
ALIAS
EGFL6L,POEM
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 255743
MIM: 610306
HGNC: 27405
Ensembl: ENSG00000168743

Variants:

dbSNP: 255743
ClinVar: 255743
TCGA: ENSG00000168743
COSMIC: NPNT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168743ENST00000305572Q6UXI9
ENSG00000168743ENST00000379987Q6UXI9
ENSG00000168743ENST00000427316Q6UXI9
ENSG00000168743ENST00000453617Q6UXI9
ENSG00000168743ENST00000503451D6RH31
ENSG00000168743ENST00000504304D6RE63
ENSG00000168743ENST00000504787H0Y8M1
ENSG00000168743ENST00000505917H0YA60
ENSG00000168743ENST00000506666Q6UXI9
ENSG00000168743ENST00000514622Q6UXI9
ENSG00000168743ENST00000514837H0YAK9

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368705482023LncRNA ADAMTS9-AS1 inhibits the stemness of lung adenocarcinoma cells by regulating miR-5009-3p/NPNT axis.5
368705482023LncRNA ADAMTS9-AS1 inhibits the stemness of lung adenocarcinoma cells by regulating miR-5009-3p/NPNT axis.5
352469782022A null founder variant in NPNT, encoding nephronectin, causes autosomal recessive renal agenesis.2
353042392022Integrated analysis identified NPNT as a potential key regulator in tumor metastasis of hepatocellular carcinoma.3
362925722022Missense Variants in GFRA1 and NPNT Are Associated with Congenital Anomalies of the Kidney and Urinary Tract.1
352469782022A null founder variant in NPNT, encoding nephronectin, causes autosomal recessive renal agenesis.2
353042392022Integrated analysis identified NPNT as a potential key regulator in tumor metastasis of hepatocellular carcinoma.3
362925722022Missense Variants in GFRA1 and NPNT Are Associated with Congenital Anomalies of the Kidney and Urinary Tract.1
340499602021A Biallelic Frameshift Mutation in Nephronectin Causes Bilateral Renal Agenesis in Humans.7
347162422021Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis.12
340499602021A Biallelic Frameshift Mutation in Nephronectin Causes Bilateral Renal Agenesis in Humans.7
347162422021Glomerular Endothelial Cell-Derived microRNA-192 Regulates Nephronectin Expression in Idiopathic Membranous Glomerulonephritis.12
329358512020Nephronectin is a prognostic biomarker and promotes gastric cancer cell proliferation, migration and invasion.2
329358512020Nephronectin is a prognostic biomarker and promotes gastric cancer cell proliferation, migration and invasion.2
311306972019Role of Nephronectin in Pathophysiology of Silicosis.8

Citation

Dessen P

NPNT (nephronectin)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50401/meetings/haematological-explorer/