MAP7 (microtubule associated protein 7)

2008-10-01  

Identity

HGNC
MAP7
LOCATION
6q23.3
LOCUSID
9053
ALIAS
E-MAP-115,EMAP115
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9053
MIM: 604108
HGNC: 6869
Ensembl: ENSG00000135525

Variants:

dbSNP: 9053
ClinVar: 9053
TCGA: ENSG00000135525
COSMIC: MAP7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135525ENST00000354570Q14244
ENSG00000135525ENST00000432797Q14244
ENSG00000135525ENST00000438100Q14244
ENSG00000135525ENST00000454590Q14244
ENSG00000135525ENST00000544465Q14244
ENSG00000135525ENST00000611373Q14244
ENSG00000135525ENST00000616617Q14244
ENSG00000135525ENST00000617204A0A087WZ40
ENSG00000135525ENST00000618822Q14244

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
384317152024A structural and dynamic visualization of the interaction between MAP7 and microtubules.1
384317152024A structural and dynamic visualization of the interaction between MAP7 and microtubules.1
350506572022Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7.38
356335462022Clinical Significance of MAP-7 and FOXC1 in Egyptian Acute Myeloid Leukemia Patients.0
362611822022MAP7 Promotes Breast Cancer Cell Migration and Invasion by Regulating the NF-B Pathway.0
350506572022Structural and functional insight into regulation of kinesin-1 by microtubule-associated protein MAP7.38
356335462022Clinical Significance of MAP-7 and FOXC1 in Egyptian Acute Myeloid Leukemia Patients.0
362611822022MAP7 Promotes Breast Cancer Cell Migration and Invasion by Regulating the NF-B Pathway.0
334492272021Plasma Exosomal CircNEK9 Accelerates the Progression of Gastric Cancer via miR-409-3p/MAP7 Axis.22
334492272021Plasma Exosomal CircNEK9 Accelerates the Progression of Gastric Cancer via miR-409-3p/MAP7 Axis.22
324463912020MAP7 interacts with RC3H1 and cooperatively regulate cell-cycle progression of cervical cancer cells via activating the NF-κB signaling.9
324463912020MAP7 interacts with RC3H1 and cooperatively regulate cell-cycle progression of cervical cancer cells via activating the NF-κB signaling.9
307704342019MAP7 family proteins regulate kinesin-1 recruitment and activation.66
307704342019MAP7 family proteins regulate kinesin-1 recruitment and activation.66
298807102018Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling.13

Citation

Dessen P

MAP7 (microtubule associated protein 7)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50426/gene-explorer/gene-fusions-explorer/