KRT15 (keratin 15)

2008-12-01  

Identity

HGNC
KRT15
LOCATION
17q21.2
LOCUSID
3866
ALIAS
CK15,K15,K1CO
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3866
MIM: 148030
HGNC: 6421
Ensembl: ENSG00000171346

Variants:

dbSNP: 3866
ClinVar: 3866
TCGA: ENSG00000171346
COSMIC: KRT15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171346ENST00000254043P19012
ENSG00000171346ENST00000393974A8MT21
ENSG00000171346ENST00000393976P19012
ENSG00000171346ENST00000458290C9JTG5
ENSG00000171346ENST00000470004K7EQK9
ENSG00000171346ENST00000497016K7EMX0

Expression (GTEx)

0
100
200
300
400
500
600
700
800
900
1000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372438442024Tumor keratin 15 expression links with less extent of invasion and better prognosis in papillary thyroid cancer patients receiving tumor resection.0
372438442024Tumor keratin 15 expression links with less extent of invasion and better prognosis in papillary thyroid cancer patients receiving tumor resection.0
354778192022KRT15 promotes colorectal cancer cell migration and invasion through β-catenin/MMP-7 signaling pathway.3
358667772022Upregulated keratin 15 links to the occurrence of lymphovascular invasion, stromal cervical invasion as well as unfavorable survival profile in endometrial cancer patients.2
354778192022KRT15 promotes colorectal cancer cell migration and invasion through β-catenin/MMP-7 signaling pathway.3
358667772022Upregulated keratin 15 links to the occurrence of lymphovascular invasion, stromal cervical invasion as well as unfavorable survival profile in endometrial cancer patients.2
317977242020Potential regulatory SNPs in the ATXN7L3B and KRT15 genes are associated with gender-specific colorectal cancer risk.3
318848022020KRT15 overexpression predicts poor prognosis in colorectal cancer.15
324496212020KRT 15 as a prognostic biomarker is highly expressed in esophageal carcinoma.3
317977242020Potential regulatory SNPs in the ATXN7L3B and KRT15 genes are associated with gender-specific colorectal cancer risk.3
318848022020KRT15 overexpression predicts poor prognosis in colorectal cancer.15
324496212020KRT 15 as a prognostic biomarker is highly expressed in esophageal carcinoma.3
316262022019Immunohistochemical study of Ki-67, PHH3, and CK15 protein expression in oral epithelial malignancy.1
316262022019Immunohistochemical study of Ki-67, PHH3, and CK15 protein expression in oral epithelial malignancy.1
277972212016Cytokeratin 15 is an Effective Indicator for Progression and Malignancy of Esophageal Squamous Cell Carcinomas.5

Citation

Dessen P

KRT15 (keratin 15)

Atlas Genet Cytogenet Oncol Haematol. 2008-12-01

Online version: http://atlasgeneticsoncology.org/gene/50481/css/lib/cancer-prone-explorer/