CUL9 (cullin 9)

2009-01-01 Affiliation

Identity

HGNC

CUL9

LOCATION

6p21.1

LOCUSID

23113

ALIAS

H7AP1,PARC

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 23113
MIM: 607489
HGNC: 15982
Ensembl: ENSG00000112659

Variants:

dbSNP: 23113
ClinVar: 23113
TCGA: ENSG00000112659
COSMIC: CUL9

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000112659	ENST00000252050	Q8IWT3
ENSG00000112659	ENST00000372647	E9PEZ1
ENSG00000112659	ENST00000502719	H0Y8H9
ENSG00000112659	ENST00000506830	H0YA00

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
33705438	2021	A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.	3
33705438	2021	A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.	3
28481879	2017	Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53.	13
28481879	2017	Cytoplasmic E3 ubiquitin ligase CUL9 controls cell proliferation, senescence, apoptosis and genome integrity through p53.	13
25028716	2014	Killing the Killer: PARC/CUL9 promotes cell survival by destroying cytochrome C.	3
25028717	2014	The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.	33
25028716	2014	Killing the Killer: PARC/CUL9 promotes cell survival by destroying cytochrome C.	3
25028717	2014	The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.	33
22117079	2012	Calpain-mediated processing of p53-associated parkin-like cytoplasmic protein (PARC) affects chemosensitivity of human ovarian cancer cells by promoting p53 subcellular trafficking.	23
22117079	2012	Calpain-mediated processing of p53-associated parkin-like cytoplasmic protein (PARC) affects chemosensitivity of human ovarian cancer cells by promoting p53 subcellular trafficking.	23
19851296	2010	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	7
20198315	2010	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	17
19851296	2010	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	7
20198315	2010	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	17
18230339	2008	Activation of p53-dependent responses in tumor cells treated with a PARC-interacting peptide.	4

Citation

Dessen P

CUL9 (cullin 9)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50656/css/humanGenome