FAM120A (family with sequence similarity 120A)

2009-05-01  

Identity

HGNC
FAM120A
LOCATION
9q22.31
LOCUSID
23196
ALIAS
C9orf10,HBVPTPAP,OSSA
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23196
MIM: 612265
HGNC: 13247
Ensembl: ENSG00000048828

Variants:

dbSNP: 23196
ClinVar: 23196
TCGA: ENSG00000048828
COSMIC: FAM120A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000048828ENST00000277165Q9NZB2
ENSG00000048828ENST00000375389Q9NZB2
ENSG00000048828ENST00000427765A0A0C4DG79
ENSG00000048828ENST00000446420A0A0C4DH52
ENSG00000048828ENST00000652239A0A494C0Y9

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383399712024C9orf10/Ossa regulates the bone metastasis of established lung adenocarcinoma cell subline H322L-BO4 in a mouse model.0
385659402024FAM120A deficiency improves resistance to cisplatin in gastric cancer by promoting ferroptosis.0
383399712024C9orf10/Ossa regulates the bone metastasis of established lung adenocarcinoma cell subline H322L-BO4 in a mouse model.0
385659402024FAM120A deficiency improves resistance to cisplatin in gastric cancer by promoting ferroptosis.0
375955592023FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1.2
375955592023FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1.2
344499472021circFAM120A participates in repeated implantation failure by regulating decidualization via the miR-29/ABHD5 axis.4
344499472021circFAM120A participates in repeated implantation failure by regulating decidualization via the miR-29/ABHD5 axis.4
277568052016Widespread structural brain involvement in ALS is not limited to the C9orf72 repeat expansion.46
277568052016Widespread structural brain involvement in ALS is not limited to the C9orf72 repeat expansion.46
258963272015IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.47
259537832015A genome-wide association study of body mass index across early life and childhood.64
258963272015IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.47
259537832015A genome-wide association study of body mass index across early life and childhood.64
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

FAM120A (family with sequence similarity 120A)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50866/gene-fusions/favicon/meetings/