MB (myoglobin)

2009-08-01  

Identity

HGNC
MB
LOCATION
22q12.3
LOCUSID
4151
ALIAS
PVALB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4151
MIM: 160000
HGNC: 6915
Ensembl: ENSG00000198125

Variants:

dbSNP: 4151
ClinVar: 4151
TCGA: ENSG00000198125
COSMIC: MB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198125ENST00000359787P02144
ENSG00000198125ENST00000359787A0A1K0FU49
ENSG00000198125ENST00000397326P02144
ENSG00000198125ENST00000397326A0A1K0FU49
ENSG00000198125ENST00000397328P02144
ENSG00000198125ENST00000397328A0A1K0FU49
ENSG00000198125ENST00000401702Q8WVH6
ENSG00000198125ENST00000406324P02144
ENSG00000198125ENST00000406324A0A1K0FU49
ENSG00000198125ENST00000419229F2Z337
ENSG00000198125ENST00000442617B0QYF7
ENSG00000198125ENST00000443033B0QYF8
ENSG00000198125ENST00000447607F2Z2F1
ENSG00000198125ENST00000451685F2Z2F1

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
9000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
376431912023Comparative analysis of the myoglobin gene in whales and humans reveals evolutionary changes in regulatory elements and expression levels.0
377594632023Myoglobin in Brown Adipose Tissue: A Multifaceted Player in Thermogenesis.2
376431912023Comparative analysis of the myoglobin gene in whales and humans reveals evolutionary changes in regulatory elements and expression levels.0
377594632023Myoglobin in Brown Adipose Tissue: A Multifaceted Player in Thermogenesis.2
346792182022Pseudoperoxidase activity, conformational stability, and aggregation propensity of the His98Tyr myoglobin variant: implications for the onset of myoglobinopathy.1
349722402022GAPDH is involved in the heme-maturation of myoglobin and hemoglobin.17
346792182022Pseudoperoxidase activity, conformational stability, and aggregation propensity of the His98Tyr myoglobin variant: implications for the onset of myoglobinopathy.1
349722402022GAPDH is involved in the heme-maturation of myoglobin and hemoglobin.17
329578722021Protective Potential of Uric Acid, Folic Acid, Glutathione and Ascorbic Acid Against the Formation of Toxic Met-Myoglobin.2
346713192021Myoglobin Protects Breast Cancer Cells Due to Its ROS and NO Scavenging Properties.5
329578722021Protective Potential of Uric Acid, Folic Acid, Glutathione and Ascorbic Acid Against the Formation of Toxic Met-Myoglobin.2
346713192021Myoglobin Protects Breast Cancer Cells Due to Its ROS and NO Scavenging Properties.5
318942492020The role of myoglobin in epithelial cancers: Insights from transcriptomics.13
320062092020Myoglobin for Detection of High-Risk Patients with Acute Myocarditis.9
322604012020Molecular Dynamics Simulation and Kinetic Study of Fluoride Binding to V21C/V66C Myoglobin with a Cytoglobin-like Disulfide Bond.2

Citation

Dessen P

MB (myoglobin)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51046/meetings/img/teaching-explorer/