MBP (myelin basic protein)

2010-01-01  

Identity

HGNC
MBP
LOCATION
18q23
LOCUSID
4155
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4155
MIM: 159430
HGNC: 6925
Ensembl: ENSG00000197971

Variants:

dbSNP: 4155
ClinVar: 4155
TCGA: ENSG00000197971
COSMIC: MBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197971ENST00000354542F8WEU6
ENSG00000197971ENST00000355994P02686
ENSG00000197971ENST00000355994A0A024R384
ENSG00000197971ENST00000359645P02686
ENSG00000197971ENST00000382582P02686
ENSG00000197971ENST00000397860P02686
ENSG00000197971ENST00000397863P02686
ENSG00000197971ENST00000397865P02686
ENSG00000197971ENST00000397866P02686
ENSG00000197971ENST00000397869H7BYR8
ENSG00000197971ENST00000397875A8MZH3
ENSG00000197971ENST00000447114C9J6H1
ENSG00000197971ENST00000459948H0YEA2
ENSG00000197971ENST00000473302E9PMR5
ENSG00000197971ENST00000483025F5H7N4
ENSG00000197971ENST00000493623H0YF02
ENSG00000197971ENST00000498683E9PNZ1
ENSG00000197971ENST00000526111E9PJ72
ENSG00000197971ENST00000527041E9PKX9
ENSG00000197971ENST00000527975E9PLU9
ENSG00000197971ENST00000528160E9PQE7
ENSG00000197971ENST00000531144E9PLQ9
ENSG00000197971ENST00000533278E9PSE2
ENSG00000197971ENST00000577755J3KT34
ENSG00000197971ENST00000578193J3QL64
ENSG00000197971ENST00000578873J3QKL5
ENSG00000197971ENST00000579129J3QQK6
ENSG00000197971ENST00000580402P02686
ENSG00000197971ENST00000580402A0A024R384
ENSG00000197971ENST00000581878J3KS94
ENSG00000197971ENST00000583474E9PLQ9
ENSG00000197971ENST00000583798J3QKN5
ENSG00000197971ENST00000585201J3KT01

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
9000
10000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
364813592023Investigation of the relationship between MBP gene polymorphisms and delayed encephalopathy after acute carbon monoxide poisoning.1
375064902023Citrullination of myelin basic protein induces a Th17-cell response in healthy individuals and enhances the presentation of MBP85-99 in patients with multiple sclerosis.3
364813592023Investigation of the relationship between MBP gene polymorphisms and delayed encephalopathy after acute carbon monoxide poisoning.1
375064902023Citrullination of myelin basic protein induces a Th17-cell response in healthy individuals and enhances the presentation of MBP85-99 in patients with multiple sclerosis.3
348899952022Multiple sclerosis and myelin basic protein: insights into protein disorder and disease.33
348899952022Multiple sclerosis and myelin basic protein: insights into protein disorder and disease.33
334353852021HIV-Infected Patients: Cross Site-Specific Hydrolysis of H3 and H4 Histones and Myelin Basic Protein with Antibodies against These Three Proteins.7
338958542021Myelin basic protein and neurofilament H in postmortem cerebrospinal fluid as surrogate markers of fatal traumatic brain injury.6
344398062021Multiple Sclerosis: Enzymatic Cross Site-Specific Hydrolysis of H1 Histone by IgGs against H1, H2A, H2B, H3, H4 Histones, and Myelin Basic Protein.6
334353852021HIV-Infected Patients: Cross Site-Specific Hydrolysis of H3 and H4 Histones and Myelin Basic Protein with Antibodies against These Three Proteins.7
338958542021Myelin basic protein and neurofilament H in postmortem cerebrospinal fluid as surrogate markers of fatal traumatic brain injury.6
344398062021Multiple Sclerosis: Enzymatic Cross Site-Specific Hydrolysis of H1 Histone by IgGs against H1, H2A, H2B, H3, H4 Histones, and Myelin Basic Protein.6
312377112020The 3A6-TCR/superagonist/HLA-DR2a complex shows similar interface and reduced flexibility compared to the complex with self-peptide.0
324317042020A Polymorphism Within the MBP Gene Is Associated With a Higher Relapse Number in Male Patients of Multiple Sclerosis.1
331433552020HIV-Infected Patients: Cross Site-Specific Hydrolysis of H2a and H2b Histones and Myelin Basic Protein with Antibodies against These Three Proteins.8

Citation

Dessen P

MBP (myelin basic protein)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51260/js/teaching-explorer/deep-insight-explorer/