ZBTB18 (zinc finger and BTB domain containing 18)

2010-03-01  

Identity

HGNC
ZBTB18
LOCATION
1q44
LOCUSID
10472
ALIAS
C2H2-171,MRD22,RP58,TAZ-1,ZNF238
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10472
MIM: 608433
HGNC: 13030
Ensembl: ENSG00000179456

Variants:

dbSNP: 10472
ClinVar: 10472
TCGA: ENSG00000179456
COSMIC: ZBTB18

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179456ENST00000358704Q99592
ENSG00000179456ENST00000622512Q99592

Expression (GTEx)

0
100
200
300
400
500
600
700
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
364143812023ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.1
375250672023A novel heterozygous ZBTB18 missense mutation in a family with non-syndromic intellectual disability.0
380564332023Expanding the Clinical and Molecular Spectrum of FOXG1- and ZBTB18-Associated Neurodevelopmental Disorders.0
364143812023ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma.1
375250672023A novel heterozygous ZBTB18 missense mutation in a family with non-syndromic intellectual disability.0
380564332023Expanding the Clinical and Molecular Spectrum of FOXG1- and ZBTB18-Associated Neurodevelopmental Disorders.0
350837472022Understanding the impact of ZBTB18 missense variation on transcription factor function in neurodevelopment and disease.4
350837472022Understanding the impact of ZBTB18 missense variation on transcription factor function in neurodevelopment and disease.4
333571262021Up-regulated miR-155 is associated with poor prognosis in childhood acute lymphoblastic leukemia and promotes cell proliferation targeting ZNF238.10
336084562021The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation.2
336210642021Structure-Based Approaches to Classify the Functional Impact of ZBTB18 Missense Variants in Health and Disease.4
338927862021Identification of ZBTB18 as a novel colorectal tumor suppressor gene through genome-wide promoter hypermethylation analysis.4
333571262021Up-regulated miR-155 is associated with poor prognosis in childhood acute lymphoblastic leukemia and promotes cell proliferation targeting ZNF238.10
336084562021The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation.2
336210642021Structure-Based Approaches to Classify the Functional Impact of ZBTB18 Missense Variants in Health and Disease.4

Citation

Dessen P

ZBTB18 (zinc finger and BTB domain containing 18)

Atlas Genet Cytogenet Oncol Haematol. 2010-03-01

Online version: http://atlasgeneticsoncology.org/gene/51384/js/case-report-explorer/gene-fusions/?id=51384