LIN28A (lin-28 homolog A)

2010-04-01  

Identity

HGNC
LOCATION
1p36.11
LOCUSID
ALIAS
CSDD1,LIN-28,LIN28,ZCCHC1,lin-28A
FUSION GENES

Other Information

Locus ID:

NCBI: 79727
MIM: 611043
HGNC: 15986
Ensembl: ENSG00000131914

Variants:

dbSNP: 79727
ClinVar: 79727
TCGA: ENSG00000131914
COSMIC: LIN28A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131914ENST00000254231Q9H9Z2
ENSG00000131914ENST00000326279Q9H9Z2

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Transcriptional regulation of pluripotent stem cellsREACTOMER-HSA-452723

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381679132024Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells.0
382169642024Exosomes derived from cancer-associated fibroblasts promote tumorigenesis, metastasis and chemoresistance of colorectal cancer by upregulating circ_0067557 to target Lin28.2
384300332024Circular RNA circ_0096041 promotes osteosarcoma cell proliferation and migration via sponging miR-556-5p and regulating LIN28A expression.2
386123952024Regulating Protein-RNA Interactions: Advances in Targeting the LIN28/Let-7 Pathway.0
386362522024GNAI3 mediated by Lin28A regulates lipopolysaccharide-induced inflammation and osteogenic differentiation in periodontal stem cells by mediating the NF-κB/NLRP3 inflammasome pathway.1
387293262024Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.0
381679132024Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells.0
382169642024Exosomes derived from cancer-associated fibroblasts promote tumorigenesis, metastasis and chemoresistance of colorectal cancer by upregulating circ_0067557 to target Lin28.2
384300332024Circular RNA circ_0096041 promotes osteosarcoma cell proliferation and migration via sponging miR-556-5p and regulating LIN28A expression.2
386123952024Regulating Protein-RNA Interactions: Advances in Targeting the LIN28/Let-7 Pathway.0
386362522024GNAI3 mediated by Lin28A regulates lipopolysaccharide-induced inflammation and osteogenic differentiation in periodontal stem cells by mediating the NF-κB/NLRP3 inflammasome pathway.1
387293262024Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.0
364367982023Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression.5
366493082023LIN28 expression and function in medulloblastoma.2
366583472023Analysis of LIN28A variants in patients with Parkinson's disease.0

Citation

Dessen P

LIN28A (lin-28 homolog A)

Atlas Genet Cytogenet Oncol Haematol. 2010-04-01

Online version: http://atlasgeneticsoncology.org/gene/51415/gene-fusions/img/gene-fusions-explorer/