RBP2 (retinol binding protein 2)

2010-04-01  

Identity

HGNC
LOCATION
3q23
LOCUSID
ALIAS
CRABP-II,CRBP2,CRBPII,RBPC2

Other Information

Locus ID:

NCBI: 5948
MIM: 180280
HGNC: 9920
Ensembl: ENSG00000114113

Variants:

dbSNP: 5948
ClinVar: 5948
TCGA: ENSG00000114113
COSMIC: RBP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000114113ENST00000232217P50120
ENSG00000114113ENST00000506825D6RGE6
ENSG00000114113ENST00000511956D6RB89

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Vitamin digestion and absorptionKEGGko04977
Vitamin digestion and absorptionKEGGhsa04977
Signal TransductionREACTOMER-HSA-162582
Visual phototransductionREACTOMER-HSA-2187338
Retinoid metabolism and transportREACTOMER-HSA-975634
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of fat-soluble vitaminsREACTOMER-HSA-6806667

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
351844572022[Effect of RBP2 gene silencing on proliferation, migration and invasion of ovarian epithelial cancer SKOV3/DDP cells and its mechanism].0
351844572022[Effect of RBP2 gene silencing on proliferation, migration and invasion of ovarian epithelial cancer SKOV3/DDP cells and its mechanism].0
289702472018Chromatin remodeling: demethylating H3K4me3 of type I IFNs gene by Rbp2 through interacting with Piasy for transcriptional attenuation.4
295672082018Deciphering protein dynamics changes along the pathway of retinol uptake by cellular retinol-binding proteins 1 and 2.4
289702472018Chromatin remodeling: demethylating H3K4me3 of type I IFNs gene by Rbp2 through interacting with Piasy for transcriptional attenuation.4
295672082018Deciphering protein dynamics changes along the pathway of retinol uptake by cellular retinol-binding proteins 1 and 2.4
275242032016Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates.4
275242032016Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates.4
254788402014Structures of holo wild-type human cellular retinol-binding protein II (hCRBPII) bound to retinol and retinal.10
254788402014Structures of holo wild-type human cellular retinol-binding protein II (hCRBPII) bound to retinol and retinal.10
232245532012Tuning the electronic absorption of protein-embedded all-trans-retinal.48
232245532012Tuning the electronic absorption of protein-embedded all-trans-retinal.48
213824442011Binding affinities of CRBPI and CRBPII for 9-cis-retinoids.17
213824442011Binding affinities of CRBPI and CRBPII for 9-cis-retinoids.17
204039972010Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.35

Citation

Dessen P

RBP2 (retinol binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2010-04-01

Online version: http://atlasgeneticsoncology.org/gene/51437/meetings/hgnc