CCNY (cyclin Y)

2010-06-01  

Identity

HGNC
CCNY
LOCATION
10p11.21
LOCUSID
219771
ALIAS
C10orf9,CBCP1,CCNX,CFP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 219771
MIM: 612786
HGNC: 23354
Ensembl: ENSG00000108100

Variants:

dbSNP: 219771
ClinVar: 219771
TCGA: ENSG00000108100
COSMIC: CCNY

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108100ENST00000265375Q8ND76
ENSG00000108100ENST00000339497Q8ND76
ENSG00000108100ENST00000374704Q8ND76
ENSG00000108100ENST00000374706Q8ND76
ENSG00000108100ENST00000490012R4GN48
ENSG00000108100ENST00000493157R4GNF3

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365761662023The role of cyclin Y in normal and pathological cells.0
365761662023The role of cyclin Y in normal and pathological cells.0
320989612020AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy.19
330391462020Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling.6
331532142020Cyclin Y is expressed in Platelets and Modulates Integrin Outside-in Signaling.3
320989612020AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy.19
330391462020Cyclin Y binds and activates CDK4 to promote the G1/S phase transition in hepatocellular carcinoma cells via Rb signaling.6
331532142020Cyclin Y is expressed in Platelets and Modulates Integrin Outside-in Signaling.3
304114962019Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell.32
304114962019Fisetin decreases TET1 activity and CCNY/CDK16 promoter 5hmC levels to inhibit the proliferation and invasion of renal cancer stem cell.32
295573912018Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells.7
295573912018Cyclin Y Modulates the Proliferation, Invasion, and Metastasis of Hepatocellular Carcinoma Cells.7
283818772017The genomic dynamics during progression of lung adenocarcinomas.4
283818772017The genomic dynamics during progression of lung adenocarcinomas.4
268316582016Cyclin Y regulates the proliferation, migration, and invasion of ovarian cancer cells via Wnt signaling pathway.16

Citation

Dessen P

CCNY (cyclin Y)

Atlas Genet Cytogenet Oncol Haematol. 2010-06-01

Online version: http://atlasgeneticsoncology.org/gene/51503/js/gene-explorer/teaching-explorer/