HOTAIR (HOX transcript antisense RNA)

2010-06-01  

Identity

HGNC
HOTAIR
LOCATION
12q13.13
LOCUSID
100124700
ALIAS
HOXAS,HOXC-AS4,HOXC11-AS1,NCRNA00072

Other Information

Locus ID:

NCBI: 100124700
MIM: 611400
HGNC: 33510
Ensembl: ENSG00000228630

Variants:

dbSNP: 100124700
ClinVar: 100124700
TCGA: ENSG00000228630
COSMIC: HOTAIR

RNA/Proteins

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164713176Platinum compoundsChemicalClinicalAnnotationassociatedPD26729200
PA444818Lung NeoplasmsDiseaseClinicalAnnotationassociatedPD26729200

References

Pubmed IDYearTitleCitations
378059622024Adolescent polycystic ovary syndrome without obesity: HOTAIR rs1443512 genotype relates to fat mass and to the redistribution of fat mass on low-dose pioglitazone.0
380002012024HOTAIR: A key regulator of the Wnt/β-catenin signaling cascade in cancer progression and treatment.3
382386522024LncRNA HOTTIP as a diagnostic biomarker for acute respiratory distress syndrome in patients with sepsis and to predict the short-term clinical outcome: a case-control study.0
382506072024LncRNA HOTAIR Inhibits miR-19a-3p to Alleviate Foam Cell Formation and Inflammatory Response in Atherosclerosis.2
383348982024Potential role of the lncRNA "HOTAIR"/miRNA "206"/BDNF network in the alteration in expression of synaptic plasticity gene arc and BDNF level in sera of patients with heroin use disorder through the PI3K/AKT/mTOR pathway compared to the controls.0
383662052024Roles of HOTAIR Long Non-coding RNA in Gliomas and Other CNS Disorders.0
385875712024The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women.0
386963202024Long non-coding RNA HOTAIR: from pan-cancer analysis to colorectal cancer-related uridine metabolism.0
378059622024Adolescent polycystic ovary syndrome without obesity: HOTAIR rs1443512 genotype relates to fat mass and to the redistribution of fat mass on low-dose pioglitazone.0
380002012024HOTAIR: A key regulator of the Wnt/β-catenin signaling cascade in cancer progression and treatment.3
382386522024LncRNA HOTTIP as a diagnostic biomarker for acute respiratory distress syndrome in patients with sepsis and to predict the short-term clinical outcome: a case-control study.0
382506072024LncRNA HOTAIR Inhibits miR-19a-3p to Alleviate Foam Cell Formation and Inflammatory Response in Atherosclerosis.2
383348982024Potential role of the lncRNA "HOTAIR"/miRNA "206"/BDNF network in the alteration in expression of synaptic plasticity gene arc and BDNF level in sera of patients with heroin use disorder through the PI3K/AKT/mTOR pathway compared to the controls.0
383662052024Roles of HOTAIR Long Non-coding RNA in Gliomas and Other CNS Disorders.0
385875712024The association of FSCN1 (rs852479, rs1640233) and HOTAIR (rs920778) polymorphisms with the risk of breast cancer in Egyptian women.0

Citation

Dessen P

HOTAIR (HOX transcript antisense RNA)

Atlas Genet Cytogenet Oncol Haematol. 2010-06-01

Online version: http://atlasgeneticsoncology.org/gene/51537/js/lib/gene-fusions-explorer/