FDCSP (follicular dendritic cell secreted protein)

2011-02-01  

Identity

HGNC
FDCSP
LOCATION
4q13.3
LOCUSID
260436
ALIAS
C4orf7,FDC-SP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 260436
MIM: 607241
HGNC: 19215
Ensembl: ENSG00000181617

Variants:

dbSNP: 260436
ClinVar: 260436
TCGA: ENSG00000181617
COSMIC: FDCSP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181617ENST00000317987Q8NFU4
ENSG00000181617ENST00000317987Q540F3

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
293562412018Tumor necrosis factor-α regulates human follicular dendritic cell-secreted protein gene transcription in gingival epithelial cells.4
293562412018Tumor necrosis factor-α regulates human follicular dendritic cell-secreted protein gene transcription in gingival epithelial cells.4
265774692016Follicular dendritic cell-secreted protein may enhance osteoclastogenesis in periodontal disease.3
265774692016Follicular dendritic cell-secreted protein may enhance osteoclastogenesis in periodontal disease.3
259536612015Decreased expression of follicular dendritic cell-secreted protein correlates with increased immunoglobulin A production in the tonsils of individuals with immunoglobulin A nephropathy.9
259536612015Decreased expression of follicular dendritic cell-secreted protein correlates with increased immunoglobulin A production in the tonsils of individuals with immunoglobulin A nephropathy.9
241380992014Osteogenic differentiation of human periodontal ligament cells after transfection with recombinant lentiviral vector containing follicular dendritic cell secreted protein.3
243574062014Transfection with follicular dendritic cell secreted protein to affect phenotype expression of human periodontal ligament cells.6
241380992014Osteogenic differentiation of human periodontal ligament cells after transfection with recombinant lentiviral vector containing follicular dendritic cell secreted protein.3
243574062014Transfection with follicular dendritic cell secreted protein to affect phenotype expression of human periodontal ligament cells.6
208116732010C4orf7 contributes to ovarian cancer metastasis by promoting cancer cell migration and invasion.8
208116732010C4orf7 contributes to ovarian cancer metastasis by promoting cancer cell migration and invasion.8
175486242007Follicular dendritic cell secreted protein (FDC-SP) regulates germinal center and antibody responses.12
175486242007Follicular dendritic cell secreted protein (FDC-SP) regulates germinal center and antibody responses.12
162599542005Identification of genes preferentially expressed in periodontal ligament: specific expression of a novel secreted protein, FDC-SP.14

Citation

Dessen P

FDCSP (follicular dendritic cell secreted protein)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52066/meetings/js/gene-fusions-explorer/