STAP2 (signal transducing adaptor family member 2)

2011-02-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
BKS
FUSION GENES

Other Information

Locus ID:

NCBI: 55620
MIM: 607881
HGNC: 30430
Ensembl: ENSG00000178078

Variants:

dbSNP: 55620
ClinVar: 55620
TCGA: ENSG00000178078
COSMIC: STAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178078ENST00000594605Q9UGK3
ENSG00000178078ENST00000598443M0R0J5
ENSG00000178078ENST00000599736M0QZ60
ENSG00000178078ENST00000600324Q9UGK3
ENSG00000178078ENST00000601482M0R2W4
ENSG00000178078ENST00000601956M0QY82

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by PTK6REACTOMER-HSA-8848021
PTK6 Activates STAT3REACTOMER-HSA-8849474

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384611892024STAP-2 facilitates insulin signaling through binding to CAP/c-Cbl and regulates adipocyte differentiation.0
384611892024STAP-2 facilitates insulin signaling through binding to CAP/c-Cbl and regulates adipocyte differentiation.0
347808122022Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases.1
347808122022Signal-transducing adaptor protein-1 and protein-2 in hematopoiesis and diseases.1
284306042017Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.5
284780372017STAP-2 interacts with Pyk2 and enhances Pyk2 activity in T-cells.2
289864502017STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization.12
284306042017Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.5
284780372017STAP-2 interacts with Pyk2 and enhances Pyk2 activity in T-cells.2
289864502017STAP-2 protein promotes prostate cancer growth by enhancing epidermal growth factor receptor stabilization.12
237000422013Estrogen-related genome-based expression profiling study of uterosacral ligaments in women with pelvic organ prolapse.6
237000422013Estrogen-related genome-based expression profiling study of uterosacral ligaments in women with pelvic organ prolapse.6
222314452012STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis.11
226112432012Signal-transducing adaptor protein-2 modulates Fas-mediated T cell apoptosis by interacting with caspase-8.7
222314452012STAP-2 interacts with and modulates BCR-ABL-mediated tumorigenesis.11

Citation

Dessen P

STAP2 (signal transducing adaptor family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52081/favicon/teaching-explorer/