CHGB (chromogranin B)

2011-04-01  

Identity

HGNC
CHGB
LOCATION
20p12.3
LOCUSID
1114
ALIAS
SCG1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1114
MIM: 118920
HGNC: 1930
Ensembl: ENSG00000089199

Variants:

dbSNP: 1114
ClinVar: 1114
TCGA: ENSG00000089199
COSMIC: CHGB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000089199ENST00000378961P05060
ENSG00000089199ENST00000455042A0A0A0MT66

Expression (GTEx)

0
500
1000
1500
2000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
pituitary gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
360950792022Chromogranin B in blood serum of patients with neuroendocrine tumors.0
365112432022The mechanisms of chromogranin B-regulated Cl- homeostasis.1
360950792022Chromogranin B in blood serum of patients with neuroendocrine tumors.0
365112432022The mechanisms of chromogranin B-regulated Cl- homeostasis.1
304517322019Molecular Profiling of Pheochromocytoma and Abdominal Paraganglioma Stratified by the PASS Algorithm Reveals Chromogranin B as Associated With Histologic Prediction of Malignant Behavior.22
308877242019Serum levels of chromogranins and secretogranins correlate with the progress and severity of Parkinson's disease.4
304517322019Molecular Profiling of Pheochromocytoma and Abdominal Paraganglioma Stratified by the PASS Algorithm Reveals Chromogranin B as Associated With Histologic Prediction of Malignant Behavior.22
308877242019Serum levels of chromogranins and secretogranins correlate with the progress and severity of Parkinson's disease.4
287958742018Lack of association between the P413L variant of chromogranin B and ALS risk or age at onset: a meta-analysis.0
290988792018Regulation of circulating chromogranin B levels in heart failure.1
287958742018Lack of association between the P413L variant of chromogranin B and ALS risk or age at onset: a meta-analysis.0
290988792018Regulation of circulating chromogranin B levels in heart failure.1
280493632017Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study.0
283323692017Gender-Specific Associations between CHGB Genetic Variants and Schizophrenia in a Korean Population.6
283349922017Utility of chromogranin B compared with chromogranin A as a biomarker in Japanese patients with pancreatic neuroendocrine tumors.6

Citation

Dessen P

CHGB (chromogranin B)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52182/haematological-explorer/css/welcome