XPO4 (exportin 4)

2011-06-01  

Identity

HGNC
XPO4
LOCATION
13q12.11
LOCUSID
64328
ALIAS
exp4

Other Information

Locus ID:

NCBI: 64328
MIM: 611449
HGNC: 17796
Ensembl: ENSG00000132953

Variants:

dbSNP: 64328
ClinVar: 64328
TCGA: ENSG00000132953
COSMIC: XPO4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132953ENST00000255305Q9C0E2
ENSG00000132953ENST00000400602F2Z2X4

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
387229732024Exportin 4 DNA promoter methylation in liver fibrosis.0
387229732024Exportin 4 DNA promoter methylation in liver fibrosis.0
343885182021Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease.8
343885182021Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease.8
273064582016Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A.34
273064582016Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A.34
259111132015Multiple exportins influence thyroid hormone receptor localization.12
262938072015Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease.6
259111132015Multiple exportins influence thyroid hormone receptor localization.12
262938072015Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease.6
245976922014Exportin 4 gene expression and DNA promoter methylation status in chronic hepatitis B virus infection.8
245976922014Exportin 4 gene expression and DNA promoter methylation status in chronic hepatitis B virus infection.8
213325502011Decreased expression of XPO4 is associated with poor prognosis in hepatocellular carcinoma.15
219913352011Exportin 4 interacts with Sox9 through the HMG Box and inhibits the DNA binding of Sox9.8
213325502011Decreased expression of XPO4 is associated with poor prognosis in hepatocellular carcinoma.15

Citation

Dessen P

XPO4 (exportin 4)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52233/xpo4