TRA2A (transformer 2 alpha homolog)

2011-10-01 Affiliation

Identity

HGNC

TRA2A

LOCATION

7p15.3

LOCUSID

29896

ALIAS

AWMS1,HSU53209

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 29896
MIM: 602718
HGNC: 16645
Ensembl: ENSG00000164548

Variants:

dbSNP: 29896
ClinVar: 29896
TCGA: ENSG00000164548
COSMIC: TRA2A

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000164548	ENST00000297071	Q13595
ENSG00000164548	ENST00000297071	Q549U1
ENSG00000164548	ENST00000392502	Q13595
ENSG00000164548	ENST00000448549	F8WEH2
ENSG00000164548	ENST00000538367	Q13595
ENSG00000164548	ENST00000621813	Q13595

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Spliceosome	KEGG	ko03040
Spliceosome	KEGG	hsa03040

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
35635094	2022	Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.	2
35635094	2022	Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.	2
31912146	2020	Integrative network analysis identifies cell-specific trans regulators of m6A.	42
32372707	2020	TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.	14
31912146	2020	Integrative network analysis identifies cell-specific trans regulators of m6A.	42
32372707	2020	TRA2A-induced upregulation of LINC00662 regulates blood-brain barrier permeability by affecting ELK4 mRNA stability in Alzheimer's microenvironment.	14
30367895	2018	TRA2A promotes proliferation, migration, invasion and epithelial mesenchymal transition of glioma cells.	14
30367895	2018	TRA2A promotes proliferation, migration, invasion and epithelial mesenchymal transition of glioma cells.	14
28416606	2017	TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative Splicing.	30
28416606	2017	TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative Splicing.	30
25970345	2015	Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression.	10
25970345	2015	Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression.	10
23255807	2013	Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.	23
23255807	2013	Tra2-mediated recognition of HIV-1 5' splice site D3 as a key factor in the processing of vpr mRNA.	23
21447598	2011	Expression of tumor-promoting Cyr61 is regulated by hTRA2-β1 and acidosis.	9

Citation

Dessen P

TRA2A (transformer 2 alpha homolog)

Atlas Genet Cytogenet Oncol Haematol. 2011-10-01

Online version: http://atlasgeneticsoncology.org/gene/52439/css/js/lib/welcome