TXNL1 (thioredoxin like 1)

2011-11-01 Affiliation

Identity

HGNC

TXNL1

LOCATION

18q21.31

LOCUSID

9352

ALIAS

HEL-S-114,TRP32,TXL-1,TXNL,Txl

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9352
MIM: 603049
HGNC: 12436
Ensembl: ENSG00000091164

Variants:

dbSNP: 9352
ClinVar: 9352
TCGA: ENSG00000091164
COSMIC: TXNL1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000091164	ENST00000217515	O43396
ENSG00000091164	ENST00000217515	V9HW51
ENSG00000091164	ENST00000586262	K7ER96
ENSG00000091164	ENST00000587613	K7EML9
ENSG00000091164	ENST00000587807	K7EPB7
ENSG00000091164	ENST00000589329	K7EKG2
ENSG00000091164	ENST00000589931	K7EME7
ENSG00000091164	ENST00000590954	O43396
ENSG00000091164	ENST00000590954	V9HW51

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
24525731	2014	TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.	43
24525731	2014	TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.	43
24525731	2014	TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.	43
24525731	2014	TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer.	43
23362275	2013	Thioredoxin-related protein 32 (TRP32) specifically reduces oxidized phosphatase of regenerating liver (PRL).	16
23362275	2013	Thioredoxin-related protein 32 (TRP32) specifically reduces oxidized phosphatase of regenerating liver (PRL).	16
21290163	2011	HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.	10
21290163	2011	HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers.	10
20455272	2010	Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein.	5
20455272	2010	Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein.	5
19349277	2009	Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome.	37
19349280	2009	Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.	18
19349277	2009	Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome.	37
19349280	2009	Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.	18
17987124	2007	The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis.	11

Citation

Dessen P

TXNL1 (thioredoxin like 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-11-01

Online version: http://atlasgeneticsoncology.org/gene/52491/case-report-explorer/gene-fusions/?id=52491