RBMS3 (RNA binding motif single stranded interacting protein 3)

2012-01-01  

Identity

HGNC
RBMS3
LOCATION
3p24.1
LOCUSID
27303
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27303
MIM: 605786
HGNC: 13427
Ensembl: ENSG00000144642

Variants:

dbSNP: 27303
ClinVar: 27303
TCGA: ENSG00000144642
COSMIC: RBMS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144642ENST00000273139Q6XE24
ENSG00000144642ENST00000383766Q6XE24
ENSG00000144642ENST00000383767Q6XE24
ENSG00000144642ENST00000434693C9JIJ9
ENSG00000144642ENST00000445033C9J9B2
ENSG00000144642ENST00000452462Q6XE24
ENSG00000144642ENST00000456853Q6XE24
ENSG00000144642ENST00000636680A0A1B0GUW5
ENSG00000144642ENST00000637842A0A1B0GTI7

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164712563BisphosphonatesChemicalClinicalAnnotationassociatedPD
PA445187OsteonecrosisDiseaseClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
386189672024The RNA-binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA.1
386189672024The RNA-binding protein RBMS3 inhibits the progression of colon cancer by regulating the stability of LIMS1 mRNA.1
364140282023Disruption of RBMS3 suppresses PD-L1 and enhances antitumor immune activities and therapeutic effects of auranofin against triple-negative breast cancer.5
367691842023Expression of RBMS3 in Breast Cancer Progression.2
364140282023Disruption of RBMS3 suppresses PD-L1 and enhances antitumor immune activities and therapeutic effects of auranofin against triple-negative breast cancer.5
367691842023Expression of RBMS3 in Breast Cancer Progression.2
360757882022Comprehensive bioinformatics analysis confirms RBMS3 as the central candidate biological target for ovarian cancer.2
360757882022Comprehensive bioinformatics analysis confirms RBMS3 as the central candidate biological target for ovarian cancer.2
338451412021LncRNA MEG3 regulates breast cancer proliferation and apoptosis through miR-141-3p/RBMS3 axis.20
339104212021Tumor Suppressor Effect of RBMS3 in Breast Cancer.8
346082662021RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA.11
338451412021LncRNA MEG3 regulates breast cancer proliferation and apoptosis through miR-141-3p/RBMS3 axis.20
339104212021Tumor Suppressor Effect of RBMS3 in Breast Cancer.8
346082662021RNA binding protein RBMS3 is a common EMT effector that modulates triple-negative breast cancer progression via stabilizing PRRX1 mRNA.11
320169512020RBMS3 delays disc degeneration by inhibiting Wnt/β-catenin signaling pathway.9

Citation

Dessen P

RBMS3 (RNA binding motif single stranded interacting protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2012-01-01

Online version: http://atlasgeneticsoncology.org/gene/52537/deep-insight-explorer/tumors-explorer/teaching-explorer/