FAM168A (family with sequence similarity 168 member A)

2012-03-01  

Identity

HGNC
LOCATION
11q13.4
LOCUSID
ALIAS
KIAA0280,TCRP1
FUSION GENES

Other Information

Locus ID:

NCBI: 23201
MIM: 616316
HGNC: 28999
Ensembl: ENSG00000054965

Variants:

dbSNP: 23201
ClinVar: 23201
TCGA: ENSG00000054965
COSMIC: FAM168A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000054965ENST00000064778Q92567
ENSG00000054965ENST00000356467Q92567
ENSG00000054965ENST00000450446Q92567

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
323238332020TCRP1 induces tamoxifen resistance by promoting the activation of SGK1 in MCF‑7 cells.4
323238332020TCRP1 induces tamoxifen resistance by promoting the activation of SGK1 in MCF‑7 cells.4
312919422019FAM168A participates in the development of chronic myeloid leukemia via BCR-ABL1/AKT1/NFκB pathway.4
312919422019FAM168A participates in the development of chronic myeloid leukemia via BCR-ABL1/AKT1/NFκB pathway.4
286232902017TCRP1 transcriptionally regulated by c-Myc confers cancer chemoresistance in tongue and lung cancer.12
288596692017Epigenetic silencing of miR-493 increases the resistance to cisplatin in lung cancer by targeting tongue cancer resistance-related protein 1(TCRP1).19
286232902017TCRP1 transcriptionally regulated by c-Myc confers cancer chemoresistance in tongue and lung cancer.12
288596692017Epigenetic silencing of miR-493 increases the resistance to cisplatin in lung cancer by targeting tongue cancer resistance-related protein 1(TCRP1).19
252606572015TCRP1 contributes to cisplatin resistance by preventing Pol β degradation in lung cancer cells.9
252606572015TCRP1 contributes to cisplatin resistance by preventing Pol β degradation in lung cancer cells.9
232515252012Microarray-assisted pathway analysis identifies MT1X & NFκB as mediators of TCRP1-associated resistance to cisplatin in oral squamous cell carcinoma.19
232515252012Microarray-assisted pathway analysis identifies MT1X & NFκB as mediators of TCRP1-associated resistance to cisplatin in oral squamous cell carcinoma.19
213343292011Cloning and functional characterization of TCRP1, a novel gene mediating resistance to cisplatin in an oral squamous cell carcinoma cell line.10
213343292011Cloning and functional characterization of TCRP1, a novel gene mediating resistance to cisplatin in an oral squamous cell carcinoma cell line.10

Citation

Dessen P

FAM168A (family with sequence similarity 168 member A)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52609/img/tumors-explorer/gene-fusions/?id=52609