CD200R1 (CD200 receptor 1)

2012-08-01  

Identity

HGNC
CD200R1
LOCATION
3q13.2
LOCUSID
131450
ALIAS
CD200R,HCRTR2,MOX2R,OX2R
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 131450
MIM: 607546
HGNC: 24235
Ensembl: ENSG00000163606

Variants:

dbSNP: 131450
ClinVar: 131450
TCGA: ENSG00000163606
COSMIC: CD200R1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163606ENST00000295863H9KV32
ENSG00000163606ENST00000308611Q8TD46
ENSG00000163606ENST00000440122Q8TD46
ENSG00000163606ENST00000471858Q8TD46
ENSG00000163606ENST00000490004Q8TD46

Expression (GTEx)

0
1
2
3
4
5
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
376165752024Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy.1
383540852024Inflammatory dendritic cells restrain CD11b(+)CD4(+) CTLs via CD200R in human NSCLC.0
386921602024CD200R promotes high glucose-induced oxidative stress and damage in human retinal pigment epithelial cells by activating the mTOR signaling pathway.1
387456522024Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model.0
376165752024Exploiting the CD200-CD200R immune checkpoint axis in multiple myeloma to enhance CAR T-cell therapy.1
383540852024Inflammatory dendritic cells restrain CD11b(+)CD4(+) CTLs via CD200R in human NSCLC.0
386921602024CD200R promotes high glucose-induced oxidative stress and damage in human retinal pigment epithelial cells by activating the mTOR signaling pathway.1
387456522024Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model.0
353265062022The Role of CD200-CD200 Receptor in Human Blood and Lymphatic Endothelial Cells in the Regulation of Skin Tissue Inflammation.3
353265062022The Role of CD200-CD200 Receptor in Human Blood and Lymphatic Endothelial Cells in the Regulation of Skin Tissue Inflammation.3
333215032021Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer.2
337804662021Identification of a novel conserved signaling motif in CD200 receptor required for its inhibitory function.1
333215032021Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer.2
337804662021Identification of a novel conserved signaling motif in CD200 receptor required for its inhibitory function.1
320306892020CD200-CD200R Pathway in the Regulation of Tumor Immune Microenvironment and Immunotherapy.30

Citation

Dessen P

CD200R1 (CD200 receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2012-08-01

Online version: http://atlasgeneticsoncology.org/gene/52788/gene-fusions/js/teaching-explorer/