CYTIP (cytohesin 1 interacting protein)

2013-03-01  

Identity

HGNC
CYTIP
LOCATION
2q24.1
LOCUSID
9595
ALIAS
B3-1,CASP,CYBR,CYTHIP,HE,PSCDBP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9595
MIM: 604448
HGNC: 9506
Ensembl: ENSG00000115165

Variants:

dbSNP: 9595
ClinVar: 9595
TCGA: ENSG00000115165
COSMIC: CYTIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115165ENST00000264192O60759
ENSG00000115165ENST00000418920C9JSM2
ENSG00000115165ENST00000435117C9JNN8
ENSG00000115165ENST00000439355C9JRF8
ENSG00000115165ENST00000457793F8WF61

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
250584602014Cytohesin-associated scaffolding protein (CASP) is involved in migration and IFN-γ secretion in natural killer cells.1
250584602014Cytohesin-associated scaffolding protein (CASP) is involved in migration and IFN-γ secretion in natural killer cells.1
232230052013Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.123
234690182013In human monocyte derived dendritic cells SOCS1 interacting with CYTIP induces the degradation of CYTIP by the proteasome.0
232230052013Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.123
234690182013In human monocyte derived dendritic cells SOCS1 interacting with CYTIP induces the degradation of CYTIP by the proteasome.0
215620432011Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration.22
215620432011Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration.22
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
175775832007Sorting nexin 27 interacts with the Cytohesin associated scaffolding protein (CASP) in lymphocytes.18
175775832007Sorting nexin 27 interacts with the Cytohesin associated scaffolding protein (CASP) in lymphocytes.18
167022242006Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway.7
167022242006Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway.7
120528272002The N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP.22

Citation

Dessen P

CYTIP (cytohesin 1 interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53225/teaching-explorer/tumors-explorer/gene-fusions/?id=53225