ATG10 (autophagy related 10)

2013-07-01  

Identity

HGNC
ATG10
LOCATION
5q14.1
LOCUSID
83734
ALIAS
APG10,APG10L,pp12616
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 83734
MIM: 610800
HGNC: 20315
Ensembl: ENSG00000152348

Variants:

dbSNP: 83734
ClinVar: 83734
TCGA: ENSG00000152348
COSMIC: ATG10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152348ENST00000282185Q9H0Y0
ENSG00000152348ENST00000355178Q9H0Y0
ENSG00000152348ENST00000355178A0A024RAK8
ENSG00000152348ENST00000458350Q9H0Y0
ENSG00000152348ENST00000504770D6RBD1
ENSG00000152348ENST00000510085D6RC89
ENSG00000152348ENST00000513443Q9H0Y0
ENSG00000152348ENST00000513443A0A024RAK8
ENSG00000152348ENST00000513634D6RDX3

Expression (GTEx)

0
1
2
3
4
5
6
7
8
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Cellular responses to stressREACTOMER-HSA-2262752
MacroautophagyREACTOMER-HSA-1632852
Autophagy - otherKEGGko04136
Autophagy - otherKEGGhsa04136

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382812932024Association of ATG10 rs1864183, ATG16L1 rs2241880 and miR-126 with esophageal cancer.0
382812932024Association of ATG10 rs1864183, ATG16L1 rs2241880 and miR-126 with esophageal cancer.0
361943662023Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.4
361943662023Long noncoding RNA SNHG1 alleviates high glucose-induced vascular smooth muscle cells calcification/senescence by post-transcriptionally regulating Bhlhe40 and autophagy via Atg10.4
349619762022Analysis of rs1864182 and rs1864183 variants in ATG10 gene and antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese Guangxi population.1
359027972022The prognostic value of autophagy related genes with potential protective function in Ewing sarcoma.4
349619762022Analysis of rs1864182 and rs1864183 variants in ATG10 gene and antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese Guangxi population.1
359027972022The prognostic value of autophagy related genes with potential protective function in Ewing sarcoma.4
339046572021A study on the potential role of autophagy-related protein 10 as a biomarker for ulcerative colitis.1
339046572021A study on the potential role of autophagy-related protein 10 as a biomarker for ulcerative colitis.1
319960712020A new transcription factor ATG10S activates IFNL2 transcription by binding at an IRF1 site in HepG2 cells.1
319960712020A new transcription factor ATG10S activates IFNL2 transcription by binding at an IRF1 site in HepG2 cells.1
316922592019Potentially functional variants of autophagy-related genes are associated with the efficacy and toxicity of radiotherapy in patients with nasopharyngeal carcinoma.14
316922592019Potentially functional variants of autophagy-related genes are associated with the efficacy and toxicity of radiotherapy in patients with nasopharyngeal carcinoma.14
303196332018Differential Effects of Autophagy-Related 10 Protein on HCV Replication and Autophagy Flux Are Mediated by Its Cysteine(44) and Cysteine(135).13

Citation

Dessen P

ATG10 (autophagy related 10)

Atlas Genet Cytogenet Oncol Haematol. 2013-07-01

Online version: http://atlasgeneticsoncology.org/gene/53439/css/js/lib/case-report-explorer/