ZFYVE21 (zinc finger FYVE-type containing 21)

2013-11-01  

Identity

HGNC
LOCATION
14q32.33
LOCUSID
ALIAS
HCVP7TP1,ZF21
FUSION GENES

Other Information

Locus ID:

NCBI: 79038
MIM: 613504
HGNC: 20760
Ensembl: ENSG00000100711

Variants:

dbSNP: 79038
ClinVar: 79038
TCGA: ENSG00000100711
COSMIC: ZFYVE21

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100711ENST00000216602Q9BQ24
ENSG00000100711ENST00000311141Q9BQ24
ENSG00000100711ENST00000553512G3V2M2
ENSG00000100711ENST00000555163R4GN42
ENSG00000100711ENST00000556610G3V5D6

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
311139532019ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.20
311139532019ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes.20
233828032013The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.5
233828032013The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.5
208901232011ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.6
217681102011ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain.10
208901232011ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.6
217681102011ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain.10
206010962010Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma.13
206010962010Single-nucleotide polymorphisms in DNA-repair genes and cutaneous melanoma.13
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.9
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.9

Citation

Dessen P

ZFYVE21 (zinc finger FYVE-type containing 21)

Atlas Genet Cytogenet Oncol Haematol. 2013-11-01

Online version: http://atlasgeneticsoncology.org/gene/53575/favicon/gene-explorer/