RITA1 (RBPJ interacting and tubulin associated 1)

2014-01-01  

Identity

HGNC
RITA1
LOCATION
12q24.13
LOCUSID
84934
ALIAS
C12orf52,RITA
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84934
HGNC: 25925
Ensembl: ENSG00000139405

Variants:

dbSNP: 84934
ClinVar: 84934
TCGA: ENSG00000139405
COSMIC: RITA1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139405ENST00000548278Q96K30
ENSG00000139405ENST00000548278A0A024RBL1
ENSG00000139405ENST00000549621Q96K30
ENSG00000139405ENST00000549621A0A024RBL1
ENSG00000139405ENST00000552495Q96K30
ENSG00000139405ENST00000615042A0A087X1G3

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
357018582022RITA1 drives the growth of bladder cancer cells by recruiting TRIM25 to facilitate the proteasomal degradation of RBPJ.3
357018582022RITA1 drives the growth of bladder cancer cells by recruiting TRIM25 to facilitate the proteasomal degradation of RBPJ.3
307054082019Potential involvement of RITA in the activation of Aurora A at spindle poles during mitosis.3
313538152019RITA modulates cell migration and invasion by affecting focal adhesion dynamics.10
317665332019RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta.1
307054082019Potential involvement of RITA in the activation of Aurora A at spindle poles during mitosis.3
313538152019RITA modulates cell migration and invasion by affecting focal adhesion dynamics.10
317665332019RITA Is Expressed in Trophoblastic Cells and Is Involved in Differentiation Processes of the Placenta.1
291223592018Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.6
291223592018Prognostic impact of RITA expression in patients with anal squamous cell carcinoma treated with chemoradiotherapy.6
284873722017Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes.18
284873722017Structure-function analysis of RBP-J-interacting and tubulin-associated (RITA) reveals regions critical for repression of Notch target genes.18
254456012014RBP-J-interacting and tubulin-associated protein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma by activating the p53-Fbxw7 pathway.10
255883072014Analysis of the interaction between human RITA and Drosophila Suppressor of Hairless.5
254456012014RBP-J-interacting and tubulin-associated protein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma by activating the p53-Fbxw7 pathway.10

Citation

Dessen P

RITA1 (RBPJ interacting and tubulin associated 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53683/gene-explorer/haematological-explorer/