NAF1 (nuclear assembly factor 1 ribonucleoprotein)

2014-06-01  

Identity

HGNC
NAF1
LOCATION
4q32.2
LOCUSID
92345
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92345
MIM: 617868
HGNC: 25126
Ensembl: ENSG00000145414

Variants:

dbSNP: 92345
ClinVar: 92345
TCGA: ENSG00000145414
COSMIC: NAF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000145414ENST00000274054Q96HR8
ENSG00000145414ENST00000422287Q96HR8
ENSG00000145414ENST00000509434D6RIB3

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
368550162023Relationship between common telomere length-related genetic variations, telomere length, and risk of antituberculosis drug-induced hepatotoxicity in Chinese Han population: As assessed for causality using the updated Roussel Uclaf Causality Assessment Method.1
368550162023Relationship between common telomere length-related genetic variations, telomere length, and risk of antituberculosis drug-induced hepatotoxicity in Chinese Han population: As assessed for causality using the updated Roussel Uclaf Causality Assessment Method.1
360672022022Colorectal cancer-associated SNP rs17042479 is involved in the regulation of NAF1 promoter activity.1
360672022022Colorectal cancer-associated SNP rs17042479 is involved in the regulation of NAF1 promoter activity.1
339212542021Telomere Length and Male Fertility.12
339212542021Telomere Length and Male Fertility.12
323337492020NAF1 rs4691896 Is Significantly Associated with Coal Workers' Pneumoconiosis in a Chinese Han Population: A Case-Control Study.3
323337492020NAF1 rs4691896 Is Significantly Associated with Coal Workers' Pneumoconiosis in a Chinese Han Population: A Case-Control Study.3
303250192019Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study.20
303250192019Genetic determinants of telomere length and risk of pancreatic cancer: A PANDoRA study.20
284540862017Association between genetic variants and esophageal cancer risk.3
284540862017Association between genetic variants and esophageal cancer risk.3
275109032016Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema.106
276214392016Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters.40
275109032016Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema.106

Citation

Dessen P

NAF1 (nuclear assembly factor 1 ribonucleoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/54034/css/gene-fusions/?id=54034