ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains)

2014-08-01 Affiliation

Identity

HGNC

ILRUN

LOCATION

6p21.31

LOCUSID

64771

ALIAS

C6orf106,FP852,dJ391O22.4

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 64771
MIM: 612217
HGNC: 21215
Ensembl: ENSG00000196821

Variants:

dbSNP: 64771
ClinVar: 64771
TCGA: ENSG00000196821
COSMIC: ILRUN

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000196821	ENST00000374021	Q5TH58
ENSG00000196821	ENST00000374023	Q9H6K1
ENSG00000196821	ENST00000374023	A0A024RCW2
ENSG00000196821	ENST00000374026	Q9H6K1

References

Pubmed ID	Year	Title	Citations
33963054	2021	ILRUN Downregulates ACE2 Expression and Blocks Infection of Human Cells by SARS-CoV-2.	3
33963054	2021	ILRUN Downregulates ACE2 Expression and Blocks Infection of Human Cells by SARS-CoV-2.	3
30311108	2019	C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.	5
30677029	2019	Genetic architecture of human thinness compared to severe obesity.	39
30311108	2019	C6orf106 accelerates pancreatic cancer cell invasion and proliferation via activating ERK signaling pathway.	5
30677029	2019	Genetic architecture of human thinness compared to severe obesity.	39
29802199	2018	C6orf106 is a novel inhibitor of the interferon-regulatory factor 3-dependent innate antiviral response.	8
29802199	2018	C6orf106 is a novel inhibitor of the interferon-regulatory factor 3-dependent innate antiviral response.	8
25736925	2015	C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.	5
25953261	2015	A novel biomarker C6orf106 promotes the malignant progression of breast cancer.	7
25736925	2015	C6orf106 enhances NSCLC cell invasion by upregulating vimentin, and downregulating E-cadherin and P120ctn.	5
25953261	2015	A novel biomarker C6orf106 promotes the malignant progression of breast cancer.	7
20546612	2010	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	28
20846217	2010	Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.	10
20546612	2010	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	28

Citation

Dessen P

ILRUN (inflammation and lipid regulator with UBA-like and NBR1-like domains)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54178/css/lib/js/gene-fusions-explorer/