LRRC37B (leucine rich repeat containing 37B)

2014-08-01  

Identity

HGNC
LRRC37B
LOCATION
17q11.2
LOCUSID
114659
ALIAS
LRRC37
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 114659
MIM: 616558
HGNC: 29070
Ensembl: ENSG00000185158

Variants:

dbSNP: 114659
ClinVar: 114659
TCGA: ENSG00000185158
COSMIC: LRRC37B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185158ENST00000327564J3QSU1
ENSG00000185158ENST00000341671Q96QE4
ENSG00000185158ENST00000394713Q96QE4
ENSG00000185158ENST00000543378F5H5K1
ENSG00000185158ENST00000578674J3QLI7
ENSG00000185158ENST00000579206J3QL10
ENSG00000185158ENST00000582117J3QKM3
ENSG00000185158ENST00000583342J3QLE7
ENSG00000185158ENST00000584368J3KTP0

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
381348742023LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.2
381348742023LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.2
192917642009RNF135 mutations are not present in patients with Sotos syndrome-like features.4
192917642009RNF135 mutations are not present in patients with Sotos syndrome-like features.4

Citation

Dessen P

LRRC37B (leucine rich repeat containing 37B)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54431/js/tumors-explorer/