MID1 (midline 1)

2014-08-01  

Identity

HGNC
MID1
LOCATION
Xp22.2
LOCUSID
4281
ALIAS
BBBG1,FXY,GBBB1,MIDIN,OGS1,OS,OSX,RNF59,TRIM18,XPRF,ZNFXY
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4281
MIM: 300552
HGNC: 7095
Ensembl: ENSG00000101871

Variants:

dbSNP: 4281
ClinVar: 4281
TCGA: ENSG00000101871
COSMIC: MID1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101871ENST00000317552O15344
ENSG00000101871ENST00000317552A0A024RBV4
ENSG00000101871ENST00000380779O15344
ENSG00000101871ENST00000380779A0A024RBV4
ENSG00000101871ENST00000380780O15344
ENSG00000101871ENST00000380780A0A024RBV4
ENSG00000101871ENST00000380782O15344
ENSG00000101871ENST00000380785O15344
ENSG00000101871ENST00000380785A0A024RBV4
ENSG00000101871ENST00000380787O15344
ENSG00000101871ENST00000380787A0A024RBV4
ENSG00000101871ENST00000413894C9J453
ENSG00000101871ENST00000453318O15344
ENSG00000101871ENST00000453318A0A024RBV4
ENSG00000101871ENST00000610939A0A087X0X0
ENSG00000101871ENST00000616003A0A087X255

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Ubiquitin mediated proteolysisKEGGko04120
Ubiquitin mediated proteolysisKEGGhsa04120
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Interferon SignalingREACTOMER-HSA-913531
Interferon gamma signalingREACTOMER-HSA-877300

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382380862024Absence of the RING domain in MID1 results in patterning defects in the developing human brain.0
383925602024Erdr1 Drives Macrophage Programming via Dynamic Interplay with YAP1 and Mid1.0
387771132024Mid1 promotes synovitis in rheumatoid arthritis via ubiquitin-dependent post-translational modification.0
382380862024Absence of the RING domain in MID1 results in patterning defects in the developing human brain.0
383925602024Erdr1 Drives Macrophage Programming via Dynamic Interplay with YAP1 and Mid1.0
387771132024Mid1 promotes synovitis in rheumatoid arthritis via ubiquitin-dependent post-translational modification.0
364268652023The role of anillin/Mid1p during medial division and cytokinesis: from fission yeast to cancer cells.5
367096452023Irradiated lung cancer cell-derived exosomes modulate macrophage polarization by inhibiting MID1 via miR-4655-5p.4
368205042023B-box1 Domain of MID1 Interacts with the Ube2D1 E2 Enzyme Differently Than RING E3 Ligases.1
374983002023Opitz GBBB syndrome with total anomalous pulmonary venous connection: A new MID1 gene variant.1
364268652023The role of anillin/Mid1p during medial division and cytokinesis: from fission yeast to cancer cells.5
367096452023Irradiated lung cancer cell-derived exosomes modulate macrophage polarization by inhibiting MID1 via miR-4655-5p.4
368205042023B-box1 Domain of MID1 Interacts with the Ube2D1 E2 Enzyme Differently Than RING E3 Ligases.1
374983002023Opitz GBBB syndrome with total anomalous pulmonary venous connection: A new MID1 gene variant.1
359091272022TRIM18 is a critical regulator of viral myocarditis and organ inflammation.19

Citation

Dessen P

MID1 (midline 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54457/favicon/css/humanGenome