TXNDC11 (thioredoxin domain containing 11)

2014-08-01  

Identity

HGNC
TXNDC11
LOCATION
16p13.13
LOCUSID
51061
ALIAS
EFP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51061
MIM: 617792
HGNC: 28030
Ensembl: ENSG00000153066

Variants:

dbSNP: 51061
ClinVar: 51061
TCGA: ENSG00000153066
COSMIC: TXNDC11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153066ENST00000283033Q6PKC3
ENSG00000153066ENST00000356957Q6PKC3
ENSG00000153066ENST00000571882I3L2Z6
ENSG00000153066ENST00000575591I3L0Q4
ENSG00000153066ENST00000576969I3L1A5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA444552HypertensionDiseaseClinicalAnnotationassociatedPD
PA449899hydrochlorothiazideChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
376861742023High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.0
376861742023High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.0
361522282022Expression analysis and functional characterization of thioredoxin domain-containing protein 11.1
361522282022Expression analysis and functional characterization of thioredoxin domain-containing protein 11.1
320655822020EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.16
320655822020EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD.16
155617112005Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.27
155617112005Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.27

Citation

Dessen P

TXNDC11 (thioredoxin domain containing 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54741/img/css/deep-insight-explorer/