ZNRF4 (zinc and ring finger 4)

2014-08-01  

Identity

HGNC
ZNRF4
LOCATION
19p13.3
LOCUSID
148066
ALIAS
RNF204,SPERIZIN,Ssrzf1,spzn
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 148066
MIM: 612063
HGNC: 17726
Ensembl: ENSG00000105428

Variants:

dbSNP: 148066
ClinVar: 148066
TCGA: ENSG00000105428
COSMIC: ZNRF4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105428ENST00000222033Q8WWF5

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
286569662017E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.19
286569662017E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.19
212058302011A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis.39
212058302011A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis.39
101910881999Sperizin is a murine RING zinc-finger protein specifically expressed in Haploid germ cells.13
101910881999Sperizin is a murine RING zinc-finger protein specifically expressed in Haploid germ cells.13

Citation

Dessen P

ZNRF4 (zinc and ring finger 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54819/gene-fusions/favicon/manifest.json