ABR (ABR activator of RhoGEF and GTPase)

2003-02-01  

Identity

HGNC
ABR
LOCATION
17p13.3
LOCUSID
29
ALIAS
MDB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 29
MIM: 600365
HGNC: 81
Ensembl: ENSG00000159842

Variants:

dbSNP: 29
ClinVar: 29
TCGA: ENSG00000159842
COSMIC: ABR

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159842ENST00000291107Q12979
ENSG00000159842ENST00000302538Q12979
ENSG00000159842ENST00000536794B7Z683
ENSG00000159842ENST00000543210Q12979
ENSG00000159842ENST00000544583Q12979
ENSG00000159842ENST00000570441I3L2P5
ENSG00000159842ENST00000570525I3L2L3
ENSG00000159842ENST00000571797I3NI05
ENSG00000159842ENST00000571945I3L1U8
ENSG00000159842ENST00000572152I3L379
ENSG00000159842ENST00000572441I3L2C0
ENSG00000159842ENST00000574139I3L4Y1
ENSG00000159842ENST00000574266I3L259
ENSG00000159842ENST00000574437A0A1C7CYZ0
ENSG00000159842ENST00000574544I3L0R7
ENSG00000159842ENST00000575770A0A0D9SGD7
ENSG00000159842ENST00000575934I3L3W0

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signalling by NGFREACTOMER-HSA-166520
p75 NTR receptor-mediated signallingREACTOMER-HSA-193704
Cell death signalling via NRAGE, NRIF and NADEREACTOMER-HSA-204998
NRAGE signals death through JNKREACTOMER-HSA-193648
Signaling by Rho GTPasesREACTOMER-HSA-194315
Rho GTPase cycleREACTOMER-HSA-194840
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (12/13) signalling eventsREACTOMER-HSA-416482

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
315163092019Genomic/proteomic analyses of dexamethasone-treated human trabecular meshwork cells reveal a role for GULP1 and ABR in phagocytosis.17
315163092019Genomic/proteomic analyses of dexamethasone-treated human trabecular meshwork cells reveal a role for GULP1 and ABR in phagocytosis.17
285793912017A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells.5
285793912017A RHO Small GTPase Regulator ABR Secures Mitotic Fidelity in Human Embryonic Stem Cells.5
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
119213392002Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs.17
119213392002Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs.17

Citation

Dessen P

ABR (ABR activator of RhoGEF and GTPase)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/549/css/lib/gene-fusions-explorer/favicon/manifest.json