FKBP6 (FKBP prolyl isomerase family member 6 (inactive))

2015-02-01  

Identity

HGNC
LOCATION
7q11.23
LOCUSID
ALIAS
FKBP36
FUSION GENES

Other Information

Locus ID:

NCBI: 8468
MIM: 604839
HGNC: 3722
Ensembl: ENSG00000077800

Variants:

dbSNP: 8468
ClinVar: 8468
TCGA: ENSG00000077800
COSMIC: FKBP6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077800ENST00000252037O75344
ENSG00000077800ENST00000413573O75344
ENSG00000077800ENST00000429879F8WD36
ENSG00000077800ENST00000431982O75344
ENSG00000077800ENST00000442793C9JM01
ENSG00000077800ENST00000445032F8WD38
ENSG00000077800ENST00000648538A0A3B3IST2

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Gene Silencing by RNAREACTOMER-HSA-211000
PIWI-interacting RNA (piRNA) biogenesisREACTOMER-HSA-5601884
Cell CycleREACTOMER-HSA-1640170
MeiosisREACTOMER-HSA-1500620
Meiotic synapsisREACTOMER-HSA-1221632

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
361503892022The piRNA-pathway factor FKBP6 is essential for spermatogenesis but dispensable for control of meiotic LINE-1 expression in humans.4
361503892022The piRNA-pathway factor FKBP6 is essential for spermatogenesis but dispensable for control of meiotic LINE-1 expression in humans.4
242411652014Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population.12
242411652014Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population.12
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.61
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.61
190013792009FKBP36 is an inherent multifunctional glyceraldehyde-3-phosphate dehydrogenase inhibitor.9
190013792009FKBP36 is an inherent multifunctional glyceraldehyde-3-phosphate dehydrogenase inhibitor.9
185290142008FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes.6
185290142008FKBP36 forms complexes with clathrin and Hsp72 in spermatocytes.6
173079192007Mutation screening of the FKBP6 gene and its association study with spermatogenic impairment in idiopathic infertile men.16
173079192007Mutation screening of the FKBP6 gene and its association study with spermatogenic impairment in idiopathic infertile men.16
173079192007Mutation screening of the FKBP6 gene and its association study with spermatogenic impairment in idiopathic infertile men.16
173079192007Mutation screening of the FKBP6 gene and its association study with spermatogenic impairment in idiopathic infertile men.16
156964702005[Possible association between 278C/A single nucleotide polymorphism of FKBP6 and idiopathic azoospermia].1

Citation

Dessen P

FKBP6 (FKBP prolyl isomerase family member 6 (inactive))

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54970/js/deep-insight-explorer/