FIGN (fidgetin, microtubule severing factor)

2015-02-01  

Identity

HGNC
LOCATION
2q24.3
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 55137
MIM: 605295
HGNC: 13285
Ensembl: ENSG00000182263

Variants:

dbSNP: 55137
ClinVar: 55137
TCGA: ENSG00000182263
COSMIC: FIGN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182263ENST00000333129Q5HY92
ENSG00000182263ENST00000409634B8ZZS6

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
384212512024Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma.0
384212512024Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma.0
331628172020Fidgetin as a potential prognostic biomarker for hepatocellular carcinoma.3
331628172020Fidgetin as a potential prognostic biomarker for hepatocellular carcinoma.3
283027522017Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is Associated With Reduced Congenital Heart Disease Susceptibility.24
285342412017A Genetic Variant in FIGN Gene Reduces the Risk of Congenital Heart Disease in Han Chinese Populations.6
283027522017Lower Circulating Folate Induced by a Fidgetin Intronic Variant Is Associated With Reduced Congenital Heart Disease Susceptibility.24
285342412017A Genetic Variant in FIGN Gene Reduces the Risk of Congenital Heart Disease in Han Chinese Populations.6
226729012012Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis.29
226729012012Human Fidgetin is a microtubule severing the enzyme and minus-end depolymerase that regulates mitosis.29
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
192400612009Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.94
196806352009Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients.17
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

FIGN (fidgetin, microtubule severing factor)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54988/css/cancer-prone-explorer/