TUT1 (terminal uridylyl transferase 1, U6 snRNA-specific)

2015-03-01  

Identity

HGNC
TUT1
LOCATION
11q12.3
LOCUSID
64852
ALIAS
PAPD2,RBM21,STARPAP,TENT1,TUTase,URLC6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64852
MIM: 610641
HGNC: 26184
Ensembl: ENSG00000255508

Variants:

dbSNP: 64852
ClinVar: 64852
TCGA: ENSG00000255508
COSMIC: TUT1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000255508ENST00000496634H3BRB1

References

Pubmed IDYearTitleCitations
383649422024Star-PAP controls oncogene expression through primary miRNA 3'-end formation to regulate cellular proliferation and tumour formation.0
383649422024Star-PAP controls oncogene expression through primary miRNA 3'-end formation to regulate cellular proliferation and tumour formation.0
375631522023Mechanism of U6 snRNA oligouridylation by human TUT1.2
375631522023Mechanism of U6 snRNA oligouridylation by human TUT1.2
345761442021Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association.0
345761442021Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association.0
281514862017Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model.6
285899552017Crystal structures of U6 snRNA-specific terminal uridylyltransferase.23
289110962017Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases.21
290322012017KLHL7 promotes TUT1 ubiquitination associated with nucleolar integrity: Implications for retinitis pigmentosa.10
281514862017Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model.6
285899552017Crystal structures of U6 snRNA-specific terminal uridylyltransferase.23
289110962017Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases.21
290322012017KLHL7 promotes TUT1 ubiquitination associated with nucleolar integrity: Implications for retinitis pigmentosa.10
264969452016CstF-64 and 3'-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα.10

Citation

Dessen P

TUT1 (terminal uridylyl transferase 1, U6 snRNA-specific)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55133/gene-explorer/js/tumors-explorer/