SVIP (small VCP interacting protein)

2015-08-01  

Identity

HGNC
LOCATION
11p14.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 258010
HGNC: 25238
Ensembl: ENSG00000198168

Variants:

dbSNP: 258010
ClinVar: 258010
TCGA: ENSG00000198168
COSMIC: SVIP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198168ENST00000354193Q8NHG7

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373742832023A Determination of p97/VCP (Valosin Containing Protein) and SVIP (Small VCP Interacting Protein) Expression Patterns in Human Testis.0
374081962023Differential Expression and Function of SVIP in Breast Cancer Cell Lines and In Silico Analysis of Its Expression and Prognostic Potential in Human Breast Cancer.0
373742832023A Determination of p97/VCP (Valosin Containing Protein) and SVIP (Small VCP Interacting Protein) Expression Patterns in Human Testis.0
374081962023Differential Expression and Function of SVIP in Breast Cancer Cell Lines and In Silico Analysis of Its Expression and Prognostic Potential in Human Breast Cancer.0
334792402021SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan.26
334792402021SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan.26
306838432019SVIP alleviates CCl(4)-induced liver fibrosis via activating autophagy and protecting hepatocytes.17
306838432019SVIP alleviates CCl(4)-induced liver fibrosis via activating autophagy and protecting hepatocytes.17
283014992017SVIP regulates Z variant alpha-1 antitrypsin retro-translocation by inhibiting ubiquitin ligase gp78.9
283014992017SVIP regulates Z variant alpha-1 antitrypsin retro-translocation by inhibiting ubiquitin ligase gp78.9
240558752013Structure and expression of a novel compact myelin protein - small VCP-interacting protein (SVIP).10
241002252013Structural and mechanistic insights into the arginine/lysine-rich peptide motifs that interact with P97/VCP.7
240558752013Structure and expression of a novel compact myelin protein - small VCP-interacting protein (SVIP).10
241002252013Structural and mechanistic insights into the arginine/lysine-rich peptide motifs that interact with P97/VCP.7
219093942011SVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagy.22

Citation

Dessen P

SVIP (small VCP interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55368/gene-fusions/haematological-explorer/