ARL4C (ADP ribosylation factor like GTPase 4C)

2016-01-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
ARL7,LAK
FUSION GENES

Other Information

Locus ID:

NCBI: 10123
MIM: 604787
HGNC: 698
Ensembl: ENSG00000188042

Variants:

dbSNP: 10123
ClinVar: 10123
TCGA: ENSG00000188042
COSMIC: ARL4C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188042ENST00000339728P56559
ENSG00000188042ENST00000390645P56559
ENSG00000188042ENST00000390645A0A024R4C5

Expression (GTEx)

0
10
20
30
40
50
60
70

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371416982023Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation.1
372373732023ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer.2
371416982023Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation.1
372373732023ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer.2
346224422022RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation.14
357189752022Identification of Neural Progenitor Cell-associated Chemoradiotherapy Resistance Gene Set (ARL4C, MSN, TNFAIP6) for Prognosis of Glioma.2
363667502022ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via notch-RBP-Jκ-H3K4Me3-OSBPL5.3
346224422022RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation.14
357189752022Identification of Neural Progenitor Cell-associated Chemoradiotherapy Resistance Gene Set (ARL4C, MSN, TNFAIP6) for Prognosis of Glioma.2
363667502022ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via notch-RBP-Jκ-H3K4Me3-OSBPL5.3
337246522021ARL4C might serve as a prognostic factor and a novel therapeutic target for gastric cancer: bioinformatics analyses and biological experiments.6
337246522021ARL4C might serve as a prognostic factor and a novel therapeutic target for gastric cancer: bioinformatics analyses and biological experiments.6
319259852020ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target.15
319259852020ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target.15
303578332019ARL4C stabilized by AKT/mTOR pathway promotes the invasion of PTEN-deficient primary human glioblastoma.17

Citation

Dessen P

ARL4C (ADP ribosylation factor like GTPase 4C)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55569/js/lib/case-report-explorer/