OIT3 (oncoprotein induced transcript 3)

2015-03-01 Affiliation

Identity

HGNC

OIT3

LOCATION

10q22.1

LOCUSID

170392

ALIAS

LZP

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 170392
MIM: 609330
HGNC: 29953
Ensembl: ENSG00000138315

Variants:

dbSNP: 170392
ClinVar: 170392
TCGA: ENSG00000138315
COSMIC: OIT3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000138315	ENST00000334011	Q8WWZ8
ENSG00000138315	ENST00000622652	Q8WWZ8

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
37201744	2023	Increased OIT3 in macrophages promotes PD-L1 expression and hepatocellular carcinogenesis via NF-κB signaling.	3
37201744	2023	Increased OIT3 in macrophages promotes PD-L1 expression and hepatocellular carcinogenesis via NF-κB signaling.	3
35353239	2022	OIT3 mediates macrophage polarization and facilitates hepatocellular carcinoma progression.	7
35353239	2022	OIT3 mediates macrophage polarization and facilitates hepatocellular carcinoma progression.	7
32569156	2020	Gout inheritance in an extended Chinese family analyzed by whole-exome sequencing: A case-report.	0
32569156	2020	Gout inheritance in an extended Chinese family analyzed by whole-exome sequencing: A case-report.	0
25824785	2015	Loss of heterozygosity at the calcium regulation gene locus on chromosome 10q in human pancreatic cancer.	6
25824785	2015	Loss of heterozygosity at the calcium regulation gene locus on chromosome 10q in human pancreatic cancer.	6
18830570	2009	Liver-specific ZP domain-containing protein (LZP) as a new partner of Tamm-Horsfall protein harbors on renal tubules.	4
18830570	2009	Liver-specific ZP domain-containing protein (LZP) as a new partner of Tamm-Horsfall protein harbors on renal tubules.	4
15589826	2004	Identification and characterization of D8C, a novel domain present in liver-specific LZP, uromodulin and glycoprotein 2, mutated in familial juvenile hyperuricaemic nephropathy.	15
15589826	2004	Identification and characterization of D8C, a novel domain present in liver-specific LZP, uromodulin and glycoprotein 2, mutated in familial juvenile hyperuricaemic nephropathy.	15
12939600	2003	A novel liver-specific zona pellucida domain containing protein that is expressed rarely in hepatocellular carcinoma.	15
12939600	2003	A novel liver-specific zona pellucida domain containing protein that is expressed rarely in hepatocellular carcinoma.	15

Citation

Dessen P

OIT3 (oncoprotein induced transcript 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55650/js/lib/favicon/gene-fusions-explorer/