KRT6B (keratin 6B)

2016-08-01  

Identity

HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
CK-6B,CK6B,K6B,KRTL1,PC2,PC4

Other Information

Locus ID:

NCBI: 3854
MIM: 148042
HGNC: 6444
Ensembl: ENSG00000185479

Variants:

dbSNP: 3854
ClinVar: 3854
TCGA: ENSG00000185479
COSMIC: KRT6B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185479ENST00000252252P04259

Expression (GTEx)

0
100
200
300
400
500
600
700
800

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
KeratinizationREACTOMER-HSA-6805567

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
293573562018Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.7
295878482018Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.11
293573562018Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.7
295878482018Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.11
264646642015KRT6 interacting with notch1 contributes to progression of renal cell carcinoma, and aliskiren inhibits renal carcinoma cell lines proliferation in vitro.14
264646642015KRT6 interacting with notch1 contributes to progression of renal cell carcinoma, and aliskiren inhibits renal carcinoma cell lines proliferation in vitro.14
222646702012A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.23
230758942012The diagnostic utility of D2-40, calretinin, CK5/6, desmin and MOC-31 in the differentiation of mesothelioma from adenocarcinoma in pleural effusion cytology.20
222646702012A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.23
230758942012The diagnostic utility of D2-40, calretinin, CK5/6, desmin and MOC-31 in the differentiation of mesothelioma from adenocarcinoma in pleural effusion cytology.20
197209112009Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.104
197209112009Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.104

Citation

Dessen P

KRT6B (keratin 6B)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55886/js/lib/gene-explorer/