USP6NL (USP6 N-terminal like)

2016-10-01  

Identity

HGNC
LOCATION
10p14
LOCUSID
ALIAS
RNTRE,TRE2NL,USP6NL-IT1
FUSION GENES

Other Information

Locus ID:

NCBI: 9712
MIM: 605405
HGNC: 16858
Ensembl: ENSG00000148429

Variants:

dbSNP: 9712
ClinVar: 9712
TCGA: ENSG00000148429
COSMIC: USP6NL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148429ENST00000277575Q92738
ENSG00000148429ENST00000379237X6RAB3
ENSG00000148429ENST00000609104Q92738
ENSG00000148429ENST00000609853V9GYH2

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
330547382020USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer.4
330547382020USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer.4
296912522018High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis.40
296912522018High USP6NL Levels in Breast Cancer Sustain Chronic AKT Phosphorylation and GLUT1 Stability Fueling Aerobic Glycolysis.40
281835282017Transethnic genome-wide scan identifies novel Alzheimer's disease loci.111
281835282017Transethnic genome-wide scan identifies novel Alzheimer's disease loci.111
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
173718732007Regulation of the Rab5 GTPase-activating protein RN-tre by the dual specificity phosphatase Cdc14A in human cells.15
173718732007Regulation of the Rab5 GTPase-activating protein RN-tre by the dual specificity phosphatase Cdc14A in human cells.15
151522552004Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.125
151522552004Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases.125

Citation

Dessen P

USP6NL (USP6 N-terminal like)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/55954/deep-insight-explorer/tumors-explorer/haematological-explorer/