DAGLB (diacylglycerol lipase beta)

2016-10-01  

Identity

HGNC
DAGLB
LOCATION
7p22.1
LOCUSID
221955
ALIAS
DAGLBETA,KCCR13L
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 221955
MIM: 614016
HGNC: 28923
Ensembl: ENSG00000164535

Variants:

dbSNP: 221955
ClinVar: 221955
TCGA: ENSG00000164535
COSMIC: DAGLB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164535ENST00000297056Q8NCG7
ENSG00000164535ENST00000425398Q8NCG7
ENSG00000164535ENST00000432248C9JA85
ENSG00000164535ENST00000436575E7ET49
ENSG00000164535ENST00000454738F8WBN0

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Retrograde endocannabinoid signalingKEGGhsa04723
Retrograde endocannabinoid signalingKEGGko04723
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Effects of PIP2 hydrolysisREACTOMER-HSA-114508
Arachidonate production from DAGREACTOMER-HSA-426048
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907
Aldosterone synthesis and secretionKEGGhsa04925
Aldosterone synthesis and secretionKEGGko04925

References

Pubmed IDYearTitleCitations
294761672018A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study.5
294761672018A novel variant associated with HDL-C levels by modifying DAGLB expression levels: An annotation-based genome-wide association study.5
271157112016Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta.0
271157112016Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta.0
146100532003Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.403
146100532003Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.403

Citation

Dessen P

DAGLB (diacylglycerol lipase beta)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56298/css/case-report-explorer/