PSG1 (pregnancy specific beta-1-glycoprotein 1)

2016-10-01  

Identity

HGNC
PSG1
LOCATION
19q13.2
LOCUSID
5669
ALIAS
B1G1,CD66f,DHFRP2,FL-NCA-1/2,PBG1,PS-beta-C/D,PS-beta-G-1,PSBG-1,PSBG1,PSG95,PSGGA,PSGIIA,SP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5669
MIM: 176390
HGNC: 9514
Ensembl: ENSG00000231924

Variants:

dbSNP: 5669
ClinVar: 5669
TCGA: ENSG00000231924
COSMIC: PSG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000231924ENST00000244296P11464
ENSG00000231924ENST00000312439P11464
ENSG00000231924ENST00000403380G5E9F7
ENSG00000231924ENST00000436291P11464
ENSG00000231924ENST00000595124M0R235
ENSG00000231924ENST00000595356P11464
ENSG00000231924ENST00000595930M0QY44
ENSG00000231924ENST00000597058M0QZQ1

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378870782023Low pregnancy-specific beta-1-glycoprotein is associated with nondipper hypertension and increased risk of preeclampsia in pregnant women with newly diagnosed chronic hypertension.0
378870782023Low pregnancy-specific beta-1-glycoprotein is associated with nondipper hypertension and increased risk of preeclampsia in pregnant women with newly diagnosed chronic hypertension.0
363093852022High Expression of Pregnancy Specific Beta-1-glycoprotein 1 Is Associated With Poor Gastric Cancer Prognosis.1
363093852022High Expression of Pregnancy Specific Beta-1-glycoprotein 1 Is Associated With Poor Gastric Cancer Prognosis.1
348550882021Effect of Pregnancy Specific β1-Glycoprotein on the Replicative Potential of Naïve T Cells and Immune Memory T Cells.0
348550882021Effect of Pregnancy Specific β1-Glycoprotein on the Replicative Potential of Naïve T Cells and Immune Memory T Cells.0
322809622020Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand.13
322809622020Glycan characterization of pregnancy-specific glycoprotein 1 and its identification as a novel Galectin-1 ligand.13
299131992019Genome-wide profiling of adult human papillary and reticular fibroblasts identifies ACAN, Col XI α1, and PSG1 as general biomarkers of dermis ageing, and KANK4 as an exemplary effector of papillary fibroblast ageing, related to contractility.14
299131992019Genome-wide profiling of adult human papillary and reticular fibroblasts identifies ACAN, Col XI α1, and PSG1 as general biomarkers of dermis ageing, and KANK4 as an exemplary effector of papillary fibroblast ageing, related to contractility.14
269262662016Pregnancy-specific glycoprotein expression in normal gastrointestinal tract and in tumors detected with novel monoclonal antibodies.12
275958332016Effect of pregnancy-specific β1-glycoprotein on indoleamine-2,3-dioxygenase activity in human monocytes.1
276537442016Targeting PSG1 to enhance chemotherapeutic efficacy: new application for anti-coagulant the dicumarol.2
278170172016The effect of pregnancy-specific β1-glycoprotein 1 on the transcription factor FOXP3 expression by immunocompetent cells.2
269262662016Pregnancy-specific glycoprotein expression in normal gastrointestinal tract and in tumors detected with novel monoclonal antibodies.12

Citation

Dessen P

PSG1 (pregnancy specific beta-1-glycoprotein 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56377/teaching-explorer/deep-insight-explorer/