HAND2 (heart and neural crest derivatives expressed 2)

2016-10-01  

Identity

HGNC
LOCATION
4q34.1
LOCUSID
ALIAS
DHAND2,Hed,Thing2,bHLHa26,dHand
FUSION GENES

Other Information

Locus ID:

NCBI: 9464
MIM: 602407
HGNC: 4808
Ensembl: ENSG00000164107

Variants:

dbSNP: 9464
ClinVar: 9464
TCGA: ENSG00000164107
COSMIC: HAND2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164107ENST00000359562P61296
ENSG00000164107ENST00000503024H0YAH1
ENSG00000164107ENST00000621866A0A087WT70

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382625602024HAND2 suppresses favipiravir efficacy in treatment of Borna disease virus infection.1
382625602024HAND2 suppresses favipiravir efficacy in treatment of Borna disease virus infection.1
364162372023NONO enhances mRNA processing of super-enhancer-associated GATA2 and HAND2 genes in neuroblastoma.8
365983652023HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype.6
370738442023[Association of ventricular septal defect with rare variations of the HAND2 gene].0
380302952023Molecular Genetic Study on HAND2 Gene Promoter in Ventricular Septal Defect.0
364162372023NONO enhances mRNA processing of super-enhancer-associated GATA2 and HAND2 genes in neuroblastoma.8
365983652023HAND2 Assists MYCN Enhancer Invasion to Regulate a Noradrenergic Neuroblastoma Phenotype.6
370738442023[Association of ventricular septal defect with rare variations of the HAND2 gene].0
380302952023Molecular Genetic Study on HAND2 Gene Promoter in Ventricular Septal Defect.0
353548172022Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma.15
361778582022Genetic evaluation of HAND2 gene and its effects on thalidomide embryopathy.0
353548172022Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma.15
361778582022Genetic evaluation of HAND2 gene and its effects on thalidomide embryopathy.0
340143712021HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.7

Citation

Dessen P

HAND2 (heart and neural crest derivatives expressed 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56467/favicon/case-report-explorer/