CD207 (CD207 molecule)

2016-10-01  

Identity

HGNC
LOCATION
2p13.3
LOCUSID
ALIAS
CLEC4K

Other Information

Locus ID:

NCBI: 50489
MIM: 604862
HGNC: 17935
Ensembl: ENSG00000116031

Variants:

dbSNP: 50489
ClinVar: 50489
TCGA: ENSG00000116031
COSMIC: CD207

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116031ENST00000410009Q9UJ71

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing-Cross presentationREACTOMER-HSA-1236975
Cross-presentation of soluble exogenous antigens (endosomes)REACTOMER-HSA-1236978

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
349352122022Origin of langerin (CD207)-expressing antigen presenting cells in the normal oral mucosa and in oral lichen planus lesions.1
349352122022Origin of langerin (CD207)-expressing antigen presenting cells in the normal oral mucosa and in oral lichen planus lesions.1
339896342021The molecular basis for the pH-dependent calcium affinity of the pattern recognition receptor langerin.4
339896342021The molecular basis for the pH-dependent calcium affinity of the pattern recognition receptor langerin.4
311418122020A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus.5
316077452020Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells.7
311418122020A Common Genetic Variation in Langerin (CD207) Compromises Cellular Uptake of Staphylococcus aureus.5
316077452020Langerin (CD207) represents a novel interferon-stimulated gene in Langerhans cells.7
296310572018High affinity sugar ligands of C-type lectin receptor langerin.10
296310572018High affinity sugar ligands of C-type lectin receptor langerin.10
264566912017Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells.22
279036352017Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent.16
281980862017Calcium-Independent Activation of an Allosteric Network in Langerin by Heparin Oligosaccharides.7
288479972017CD207(+)CD1a(+) cells circulate in pediatric patients with active Langerhans cell histiocytosis.16
264566912017Langerin-mediated internalization of a modified peptide routes antigens to early endosomes and enhances cross-presentation by human Langerhans cells.22

Citation

Dessen P

CD207 (CD207 molecule)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56545/js/lib/gene-explorer/