AQP7 (aquaporin 7)

2017-04-01 Affiliation

Identity

HGNC

AQP7

LOCATION

9p13.3

LOCUSID

364

ALIAS

AQP7L,AQPap,GLYCQTL

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 364
MIM: 602974
HGNC: 640
Ensembl: ENSG00000165269

Variants:

dbSNP: 364
ClinVar: 364
TCGA: ENSG00000165269
COSMIC: AQP7

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000165269	ENST00000297988	O14520
ENSG00000165269	ENST00000377425	Q6P5T0
ENSG00000165269	ENST00000379506	Q5T5M0
ENSG00000165269	ENST00000379507	Q5T5M1
ENSG00000165269	ENST00000439678	Q5T5L3
ENSG00000165269	ENST00000447660	O14520
ENSG00000165269	ENST00000537089	A0A096LNU3
ENSG00000165269	ENST00000624005	A0A096LNU3
ENSG00000165269	ENST00000624075	B7Z4U2
ENSG00000165269	ENST00000624095	A0A096LP64
ENSG00000165269	ENST00000624420	A0A096LP23
ENSG00000165269	ENST00000624890	A0A096LNN5
ENSG00000165269	ENST00000625032	A0A096LNV7
ENSG00000165269	ENST00000625109	A0A096LNK2

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
PPAR signaling pathway	KEGG	ko03320
PPAR signaling pathway	KEGG	hsa03320
Regulation of lipolysis in adipocytes	KEGG	hsa04923
Transmembrane transport of small molecules	REACTOME	R-HSA-382551
Aquaporin-mediated transport	REACTOME	R-HSA-445717
Passive transport by Aquaporins	REACTOME	R-HSA-432047
Transport of glycerol from adipocytes to the liver by Aquaporins	REACTOME	R-HSA-432030

References

Pubmed ID	Year	Title	Citations
36737436	2023	Cryo-EM structure supports a role of AQP7 as a junction protein.	5
37566082	2023	Aquaporin-7-Mediated Glycerol Permeability Is Linked to Human Sperm Motility in Asthenozoospermia and during Sperm Capacitation.	0
36737436	2023	Cryo-EM structure supports a role of AQP7 as a junction protein.	5
37566082	2023	Aquaporin-7-Mediated Glycerol Permeability Is Linked to Human Sperm Motility in Asthenozoospermia and during Sperm Capacitation.	0
34627746	2022	Aquaglyceroporins and orthodox aquaporins in human adipocytes.	9
35076928	2022	[Association study of single nucleotide polymorphisms of AQP7 and AQP9 genes with type 2 diabetes mellitus among ethnic Han Chinese population].	0
35366004	2022	Cholecystokinin promotes functional expression of the aquaglycerol channel aquaporin 7 in adipocytes.	0
34627746	2022	Aquaglyceroporins and orthodox aquaporins in human adipocytes.	9
35076928	2022	[Association study of single nucleotide polymorphisms of AQP7 and AQP9 genes with type 2 diabetes mellitus among ethnic Han Chinese population].	0
35366004	2022	Cholecystokinin promotes functional expression of the aquaglycerol channel aquaporin 7 in adipocytes.	0
33579525	2021	Different expression and localization of aquaporin 7 and aquaporin 9 in granulosa cells, oocytes, and embryos of patients with polycystic ovary syndrome and the negatively correlated relationship with insulin regulation.	0
33652340	2021	Association of Aquaporin-3, Aquaporin-7, NOS3 and CYBA polymorphisms with hypertensive disorders in women.	3
33579525	2021	Different expression and localization of aquaporin 7 and aquaporin 9 in granulosa cells, oocytes, and embryos of patients with polycystic ovary syndrome and the negatively correlated relationship with insulin regulation.	0
33652340	2021	Association of Aquaporin-3, Aquaporin-7, NOS3 and CYBA polymorphisms with hypertensive disorders in women.	3
31831212	2020	Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7.	16

Citation

Dessen P

AQP7 (aquaporin 7)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56897/js/lib/humanGenome