C17orf49 (chromosome 17 open reading frame 49)

2017-08-01  

Identity

HGNC
LOCATION
17p13.1
LOCUSID
ALIAS
BAP18,HEPIS
FUSION GENES

Other Information

Locus ID:

NCBI: 124944
MIM: 617215
HGNC: 28737
Ensembl: ENSG00000258315

Variants:

dbSNP: 124944
ClinVar: 124944
TCGA: ENSG00000258315
COSMIC: C17orf49

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000258315ENST00000439424Q8IXM2
ENSG00000258315ENST00000546495Q8IXM2
ENSG00000258315ENST00000546760F8W038
ENSG00000258315ENST00000547747K7ES76
ENSG00000258315ENST00000552402Q8IXM2
ENSG00000258315ENST00000552775F8W1H0

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380423102024BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression.0
380423102024BAP18 acting as a novel peroxisome proliferator-activated receptor α co-regulator contributes to hepatocellular carcinoma progression.0
368289162023BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer.0
368289162023BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer.0
355870572022BAP18 induces growth of non-small-cell lung carcinoma through upregulating transcriptional level of CCND1/2.1
355870572022BAP18 induces growth of non-small-cell lung carcinoma through upregulating transcriptional level of CCND1/2.1
321131622020BAP18 is involved in upregulation of CCND1/2 transcription to promote cell growth in oral squamous cell carcinoma.6
329868412020An H3K4me3 reader, BAP18 as an adaptor of COMPASS-like core subunits co-activates ERα action and associates with the sensitivity of antiestrogen in breast cancer.10
321131622020BAP18 is involved in upregulation of CCND1/2 transcription to promote cell growth in oral squamous cell carcinoma.6
329868412020An H3K4me3 reader, BAP18 as an adaptor of COMPASS-like core subunits co-activates ERα action and associates with the sensitivity of antiestrogen in breast cancer.10
272264922016BAP18 coactivates androgen receptor action and promotes prostate cancer progression.0
272264922016BAP18 coactivates androgen receptor action and promotes prostate cancer progression.0

Citation

Dessen P

C17orf49 (chromosome 17 open reading frame 49)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56925/gene-fusions/hgnc